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Pex13 peroxisomal biogenesis factor 13 [ Mus musculus (house mouse) ]

Gene ID: 72129, updated on 8-Feb-2024

Summary

Official Symbol
Pex13provided by MGI
Official Full Name
peroxisomal biogenesis factor 13provided by MGI
Primary source
MGI:MGI:1919379
See related
Ensembl:ENSMUSG00000020283 AllianceGenome:MGI:1919379
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610008O20Rik
Summary
Predicted to enable peroxisome targeting sequence binding activity. Acts upstream of or within several processes, including fatty acid alpha-oxidation; microtubule-based peroxisome localization; and nervous system development. Located in peroxisomal membrane. Is expressed in brain and liver. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 11A. Orthologous to human PEX13 (peroxisomal biogenesis factor 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 13.1), adrenal adult (RPKM 11.3) and 28 other tissues See more
Orthologs
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Genomic context

See Pex13 in Genome Data Viewer
Location:
11 A3.2; 11 14.34 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (23597283..23615883, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (23646843..23665883, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_28917 Neighboring gene selenoprotein K, pseudogene 1 Neighboring gene SANT and BTB domain regulator of CSR Neighboring gene pseudouridylate synthase 10 Neighboring gene STARR-seq mESC enhancer starr_28923 Neighboring gene reticuloendotheliosis oncogene Neighboring gene STARR-seq mESC enhancer starr_28924 Neighboring gene predicted gene, 39612

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peroxisome targeting sequence binding TAS
Traceable Author Statement
more info
PubMed 
enables protein transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of peroxisomal importomer complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in peroxisomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in peroxisomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in peroxisomal membrane ISO
Inferred from Sequence Orthology
more info
 
located_in peroxisome IDA
Inferred from Direct Assay
more info
PubMed 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
peroxisomal membrane protein PEX13
Names
peroxin-13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023651.5NP_076140.2  peroxisomal membrane protein PEX13

    See identical proteins and their annotated locations for NP_076140.2

    Status: VALIDATED

    Source sequence(s)
    AL672049
    Consensus CDS
    CCDS24478.1
    UniProtKB/Swiss-Prot
    Q3U5T1, Q8CCJ5, Q8CCW5, Q99MM2, Q9D0K1, Q9EPK1
    Related
    ENSMUSP00000020523.4, ENSMUST00000020523.4
    Conserved Domains (2) summary
    cd11864
    Location:278335
    SH3_PEX13_eumet; Src Homology 3 domain of eumetazoan Peroxisomal biogenesis factor 13
    pfam04088
    Location:113256
    Peroxin-13_N; Peroxin 13, N-terminal region

RNA

  1. NR_157299.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK031975, AK032650, BB856772, BF016908

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    23597283..23615883 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)