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Phf7 PHD finger protein 7 [ Mus musculus (house mouse) ]

Gene ID: 71838, updated on 1-Mar-2024

Summary

Official Symbol
Phf7provided by MGI
Official Full Name
PHD finger protein 7provided by MGI
Primary source
MGI:MGI:1919088
See related
Ensembl:ENSMUSG00000021902 AllianceGenome:MGI:1919088
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700006H01Rik; 1700010P14Rik
Summary
Predicted to enable metal ion binding activity. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and nuclear speck. Predicted to be active in nucleus. Orthologous to human PHF7 (PHD finger protein 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 488.0) See more
Orthologs
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Genomic context

See Phf7 in Genome Data Viewer
Location:
14 B; 14 19.09 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (30959646..30973327, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (31237689..31251344, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene troponin C, cardiac/slow skeletal Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G Neighboring gene STARR-positive B cell enhancer ABC_E7302 Neighboring gene Brca1 associated protein 1 Neighboring gene dynein, axonemal, heavy chain 1 Neighboring gene predicted gene, 35823 Neighboring gene STARR-positive B cell enhancer ABC_E10823

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
PHD finger protein 7
Names
testis development protein NYD-SP6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360624.1NP_001347553.1  PHD finger protein 7 isoform 2

    Status: VALIDATED

    Source sequence(s)
    BC049113, BM937743
    Consensus CDS
    CCDS88616.1
    Related
    ENSMUSP00000154095.2, ENSMUST00000226565.2
    Conserved Domains (2) summary
    cd15669
    Location:33144
    ePHD_PHF7_G2E3_like; Extended PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
    cl22851
    Location:225261
    PHD_SF; PHD finger superfamily
  2. NM_001360625.1NP_001347554.1  PHD finger protein 7 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK005852, BC049113, BC145337, BM937743
    Consensus CDS
    CCDS88614.1
    UniProtKB/TrEMBL
    B7ZNN0
    Related
    ENSMUSP00000154738.2, ENSMUST00000228437.2
    Conserved Domains (2) summary
    cd15496
    Location:152205
    PHD_PHF7_G2E3_like; PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
    cl22851
    Location:3397
    PHD_SF; PHD finger superfamily
  3. NM_027949.2NP_082225.1  PHD finger protein 7 isoform 1

    See identical proteins and their annotated locations for NP_082225.1

    Status: VALIDATED

    Source sequence(s)
    AK005852, BC049113, BM937743
    Consensus CDS
    CCDS26909.1
    UniProtKB/Swiss-Prot
    Q6PG81, Q9DAG9
    UniProtKB/TrEMBL
    A2RTI5
    Related
    ENSMUSP00000022459.4, ENSMUST00000022459.5
    Conserved Domains (2) summary
    cd15496
    Location:247300
    PHD_PHF7_G2E3_like; PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
    cd15669
    Location:33144
    ePHD_PHF7_G2E3_like; Extended PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)

RNA

  1. NR_153760.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK005852, BC049113, BC145338, BM937743
  2. NR_153761.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC108416, AK005852, BC049113, BM937743
    Related
    ENSMUST00000226310.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    30959646..30973327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245202.4XP_011243504.1  PHD finger protein 7 isoform X1

    Conserved Domains (1) summary
    cd15669
    Location:33144
    ePHD_PHF7_G2E3_like; Extended PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)
  2. XM_011245203.4XP_011243505.1  PHD finger protein 7 isoform X2

    UniProtKB/TrEMBL
    A0A2I3BR08
    Related
    ENSMUSP00000154281.2, ENSMUST00000228930.2
    Conserved Domains (1) summary
    cd15669
    Location:33138
    ePHD_PHF7_G2E3_like; Extended PHD finger found in PHD finger protein 7 (PHF7) and G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)