Format

Send to:

Choose Destination

Fbxo9 f-box protein 9 [ Mus musculus (house mouse) ]

Gene ID: 71538, updated on 5-Aug-2018

Summary

Official Symbol
Fbxo9provided by MGI
Official Full Name
f-box protein 9provided by MGI
Primary source
MGI:MGI:1918788
See related
Ensembl:ENSMUSG00000001366 Vega:OTTMUSG00000034577
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AA986398; 9030401P18Rik
Expression
Ubiquitous expression in cerebellum adult (RPKM 35.4), adrenal adult (RPKM 26.9) and 28 other tissues See more
Orthologs

Genomic context

See Fbxo9 in Genome Data Viewer
Location:
9; 9 E1
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (78081499..78109065, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (77929306..77956860, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene glial cells missing homolog 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene intestinal cell kinase Neighboring gene RNA, 7SK, nuclear

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
fat cell differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
innate immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
regulation of TOR signaling ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SCF ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081490.2NP_001074959.1  F-box only protein 9 isoform 2

    See identical proteins and their annotated locations for NP_001074959.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. It encodes isoform 2, which has a longer and distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC159313, AI847242, AK077607, DV657928
    Consensus CDS
    CCDS52864.1
    UniProtKB/Swiss-Prot
    Q8BK06
    Related
    ENSMUSP00000001402.7, OTTMUSP00000047751, ENSMUST00000001402.13, OTTMUST00000087723
    Conserved Domains (2) summary
    pfam12937
    Location:178229
    F-box-like; F-box-like
    cl00299
    Location:82113
    MIT; MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
  2. NM_023605.2NP_076094.2  F-box only protein 9 isoform 1

    See identical proteins and their annotated locations for NP_076094.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes isoform 1.
    Source sequence(s)
    AC159313, AK077607, CX567646
    Consensus CDS
    CCDS52863.1
    UniProtKB/Swiss-Prot
    Q8BK06
    Related
    ENSMUSP00000082419.6, OTTMUSP00000047752, ENSMUST00000085311.12, OTTMUST00000087724
    Conserved Domains (2) summary
    pfam12937
    Location:177228
    F-box-like; F-box-like
    cl00299
    Location:81112
    MIT; MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    78081499..78109065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center