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Itprid2 ITPR interacting domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 70599, updated on 12-May-2024

Summary

Official Symbol
Itprid2provided by MGI
Official Full Name
ITPR interacting domain containing 2provided by MGI
Primary source
MGI:MGI:1917849
See related
Ensembl:ENSMUSG00000027007 AllianceGenome:MGI:1917849
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CS1; CS-1; KRAP; Ssfa2; SPAG13; mKIAA1927; 5730488C15Rik
Summary
Predicted to enable actin filament binding activity. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Orthologous to human ITPRID2 (ITPR interacting domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 10.2), small intestine adult (RPKM 10.1) and 28 other tissues See more
Orthologs
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Genomic context

See Itprid2 in Genome Data Viewer
Location:
2 C3; 2 47.58 cM
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (79419207..79503310)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (79588863..79672966)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 54165 Neighboring gene predicted gene, 39867 Neighboring gene STARR-positive B cell enhancer ABC_E2625 Neighboring gene STARR-seq mESC enhancer starr_04937 Neighboring gene protein phosphatase 1, regulatory inhibitor subunit 1C Neighboring gene STARR-seq mESC enhancer starr_04938 Neighboring gene STARR-seq mESC enhancer starr_04939 Neighboring gene phosphodiesterase 1A, calmodulin-dependent Neighboring gene predicted gene, 54166

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (1)  1 citation

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin filament binding ISO
Inferred from Sequence Orthology
more info
 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein ITPRID2
Names
ITPR-interacting domain-containing protein 2
ki-ras-induced actin-interacting protein
sperm specific antigen 2
sperm-specific antigen 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080558.4NP_542125.3  protein ITPRID2

    See identical proteins and their annotated locations for NP_542125.3

    Status: VALIDATED

    Source sequence(s)
    BC079535, CF539296, CJ129385
    Consensus CDS
    CCDS16170.1
    UniProtKB/Swiss-Prot
    A2AQD4, A5D8Z6, Q08E80, Q14BJ9, Q544I3, Q68FN1, Q75WU7, Q8CH96, Q8VEF7, Q922B9
    UniProtKB/TrEMBL
    A2AQD6
    Related
    ENSMUSP00000107415.3, ENSMUST00000111785.9
    Conserved Domains (2) summary
    pfam14722
    Location:146297
    KRAP_IP3R_bind; Ki-ras-induced actin-interacting protein-IP3R-interacting domain
    pfam14723
    Location:8611029
    SSFA2_C; Sperm-specific antigen 2 C-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    79419207..79503310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162564.1XP_036018457.1  protein ITPRID2 isoform X1

    UniProtKB/Swiss-Prot
    A2AQD4, A5D8Z6, Q08E80, Q14BJ9, Q544I3, Q68FN1, Q75WU7, Q8CH96, Q8VEF7, Q922B9
    UniProtKB/TrEMBL
    A2AQD6
    Conserved Domains (2) summary
    pfam14722
    Location:146297
    KRAP_IP3R_bind; Ki-ras-induced actin-interacting protein-IP3R-interacting domain
    pfam14723
    Location:8611029
    SSFA2_C; Sperm-specific antigen 2 C-terminus
  2. XM_036162565.1XP_036018458.1  protein ITPRID2 isoform X2

    UniProtKB/TrEMBL
    A2AQD5, A2AQD6
    Related
    ENSMUSP00000107414.3, ENSMUST00000111784.9
    Conserved Domains (2) summary
    pfam14722
    Location:146297
    KRAP_IP3R_bind; Ki-ras-induced actin-interacting protein-IP3R-interacting domain
    pfam14723
    Location:8611029
    SSFA2_C; Sperm-specific antigen 2 C-terminus
  3. XM_006500165.4XP_006500228.1  protein ITPRID2 isoform X3

    Conserved Domains (1) summary
    pfam14723
    Location:373539
    SSFA2_C; Sperm-specific antigen 2 C-terminus

RNA

  1. XR_001783177.2 RNA Sequence