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TCTE3 t-complex-associated-testis-expressed 3 [ Homo sapiens (human) ]

Gene ID: 6991, updated on 4-Jul-2020

Summary

Official Symbol
TCTE3provided by HGNC
Official Full Name
t-complex-associated-testis-expressed 3provided by HGNC
Primary source
HGNC:HGNC:11695
See related
Ensembl:ENSG00000184786 MIM:186977
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TCTEX2; Tctex4; TCTEX1D3
Expression
Biased expression in testis (RPKM 8.5), ovary (RPKM 0.9) and 7 other tissues See more
Orthologs

Genomic context

See TCTE3 in Genome Data Viewer
Location:
6q27
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (169725488..169751581, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (170140215..170151638, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene WD repeat domain 27 Neighboring gene chromosome 6 open reading frame 120 Neighboring gene PHD finger protein 10 Neighboring gene ER membrane associated RNA degradation Neighboring gene long intergenic non-protein coding RNA 242 Neighboring gene long intergenic non-protein coding RNA 574

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC142199

Gene Ontology Provided by GOA

Function Evidence Code Pubs
motor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
dynein complex IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tctex1 domain-containing protein 3
Names
T-complex testis-specific protein 3
T-complex-associated testis-expressed protein 3
Tctex1 domain containing 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174910.3NP_777570.1  tctex1 domain-containing protein 3

    See identical proteins and their annotated locations for NP_777570.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the protein-coding transcript.
    Source sequence(s)
    AF519569, AL354892, BX089062
    Consensus CDS
    CCDS5310.1
    UniProtKB/Swiss-Prot
    Q8IZS6
    Related
    ENSP00000355736.3, ENST00000366774.4
    Conserved Domains (2) summary
    pfam03645
    Location:100196
    Tctex-1; Tctex-1 family
    cl25363
    Location:1172
    VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)

RNA

  1. NR_138070.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) is intronless and differs in the 3' end compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    BC043594, BC063455
    Related
    ENST00000628156.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    169725488..169751581 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006715554.3XP_006715617.1  tctex1 domain-containing protein 3 isoform X2

    See identical proteins and their annotated locations for XP_006715617.1

    Conserved Domains (1) summary
    pfam03645
    Location:43136
    Tctex-1; Tctex-1 family
  2. XM_011536093.3XP_011534395.1  tctex1 domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_011534395.1

    UniProtKB/Swiss-Prot
    Q8IZS6
    Conserved Domains (2) summary
    pfam03645
    Location:100196
    Tctex-1; Tctex-1 family
    cl25363
    Location:1172
    VirB10_like; VirB10 and similar proteins form part of core complex in Type IV secretion system (T4SS)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187552.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    15311..26774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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