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TECTB tectorin beta [ Homo sapiens (human) ]

Gene ID: 6975, updated on 18-Aug-2020

Summary

Official Symbol
TECTBprovided by HGNC
Official Full Name
tectorin betaprovided by HGNC
Primary source
HGNC:HGNC:11721
See related
Ensembl:ENSG00000119913 MIM:602653
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a non-collagenous glycoprotein component of the tectorial membrane, which covers the auditory hair cells in the cochlea of the inner ear. A similar protein in mouse functions in low-frequency hearing. [provided by RefSeq, Jul 2013]
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See TECTB in Genome Data Viewer
Location:
10q25.2
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (112283400..112305038)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (114043213..114064793)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene glycerol-3-phosphate acyltransferase, mitochondrial Neighboring gene uncharacterized LOC101927600 Neighboring gene Sharpr-MPRA regulatory region 2531 Neighboring gene microRNA 6715b Neighboring gene microRNA 6715a Neighboring gene guanylate cyclase 2G, pseudogene Neighboring gene acyl-CoA synthetase long chain family member 5 Neighboring gene zinc finger DHHC-type palmitoyltransferase 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Clone Names

  • KIAA1560, MGC142057, MGC142059

Gene Ontology Provided by GOA

Function Evidence Code Pubs
extracellular matrix structural constituent IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_058222.3NP_478129.1  beta-tectorin precursor

    See identical proteins and their annotated locations for NP_478129.1

    Status: VALIDATED

    Source sequence(s)
    AL391986, BC113499
    Consensus CDS
    CCDS7571.1
    UniProtKB/Swiss-Prot
    Q96PL2
    Related
    ENSP00000494896.1, ENST00000646139.2
    Conserved Domains (1) summary
    smart00241
    Location:32283
    ZP; Zona pellucida (ZP) domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    112283400..112305038
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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