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Enho energy homeostasis associated [ Mus musculus (house mouse) ]

Gene ID: 69638, updated on 12-May-2024

Summary

Official Symbol
Enhoprovided by MGI
Official Full Name
energy homeostasis associatedprovided by MGI
Primary source
MGI:MGI:1916888
See related
Ensembl:ENSMUSG00000028445 AllianceGenome:MGI:1916888
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110065P19Rik; 2310040A07Rik
Summary
Enables hormone activity. Acts upstream of or within positive regulation of Notch signaling pathway. Located in plasma membrane. Is expressed in ductus deferens; epididymis; esophagus; ileum; and prostate gland. Orthologous to human ENHO (energy homeostasis associated). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 64.8), cerebellum adult (RPKM 41.1) and 22 other tissues See more
Orthologs
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Genomic context

See Enho in Genome Data Viewer
Location:
4 A5; 4 21.8 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (41638144..41640302, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (41638144..41640302, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 219, member A, opposite strand Neighboring gene family with sequence similarity 219, member A Neighboring gene predicted gene 12404 Neighboring gene STARR-positive B cell enhancer ABC_E659 Neighboring gene dynein axonemal intermediate chain 1 Neighboring gene STARR-seq mESC enhancer starr_10035 Neighboring gene predicted gene 12405 Neighboring gene ciliary neurotrophic factor receptor Neighboring gene STARR-seq mESC enhancer starr_10037

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hormone activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within positive regulation of Notch signaling pathway IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
adropin
Names
energy homeostasis-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027147.1NP_081423.1  adropin precursor

    See identical proteins and their annotated locations for NP_081423.1

    Status: VALIDATED

    Source sequence(s)
    AK050496, BQ030577, BQ554924
    Consensus CDS
    CCDS59655.1
    UniProtKB/Swiss-Prot
    Q8K1D8
    Related
    ENSMUSP00000137902.2, ENSMUST00000127306.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    41638144..41640302 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)