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Elf2 E74-like factor 2 [ Mus musculus (house mouse) ]

Gene ID: 69257, updated on 23-Jun-2021

Summary

Official Symbol
Elf2provided by MGI
Official Full Name
E74-like factor 2provided by MGI
Primary source
MGI:MGI:1916507
See related
Ensembl:ENSMUSG00000037174
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EU32; NERF; NERF-2; NERF-1A; NERF-1B; AW111824; BB183398; 2610036A20Rik; A230104O07Rik
Expression
Ubiquitous expression in testis adult (RPKM 16.4), thymus adult (RPKM 9.2) and 28 other tissues See more
Orthologs
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Genomic context

See Elf2 in Genome Data Viewer
Location:
3; 3 C
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (51160141..51248101, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (51252720..51340683, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (51059587..51129909, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40044 Neighboring gene nocturnin Neighboring gene RIKEN cDNA 4930577N17 gene Neighboring gene nuclear encoded tRNA proline 7 (anticodon TGG) Neighboring gene nuclear encoded tRNA proline 5 (anticodon AGG)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC102660

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ETS-related transcription factor Elf-2
Names
ets domain transcription factor
ets family transcription factor ELF2A2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291059.1NP_001277988.1  ETS-related transcription factor Elf-2 isoform 2

    See identical proteins and their annotated locations for NP_001277988.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AC118601, AC161183, AK146819
    Consensus CDS
    CCDS71242.1
    UniProtKB/Swiss-Prot
    Q9JHC9
    UniProtKB/TrEMBL
    Q3TVH6
    Related
    ENSMUSP00000061076.7, ENSMUST00000062009.14
    Conserved Domains (2) summary
    pfam00178
    Location:197277
    Ets; Ets-domain
    pfam12310
    Location:3108
    Elf-1_N; Transcription factor protein N terminal
  2. NM_001291062.1NP_001277991.1  ETS-related transcription factor Elf-2 isoform 3

    See identical proteins and their annotated locations for NP_001277991.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate 5' structure and an alternate splice site in the coding region compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC118601, AC161183, AF256218
    Consensus CDS
    CCDS71240.1
    UniProtKB/Swiss-Prot
    Q9JHC9
    Related
    ENSMUSP00000103686.2, ENSMUST00000108051.8
    Conserved Domains (2) summary
    pfam00178
    Location:138217
    Ets; Ets-domain
    pfam12310
    Location:2048
    Elf-1_N; Transcription factor protein N terminal
  3. NM_001291063.1NP_001277992.1  ETS-related transcription factor Elf-2 isoform 4

    See identical proteins and their annotated locations for NP_001277992.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate 5' structure compared to variant 1. The encoded isoform (4) is shorter and has a distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC118601, AC161183, AF256219
    Consensus CDS
    CCDS71241.1
    UniProtKB/Swiss-Prot
    Q9JHC9
    Related
    ENSMUSP00000103688.3, ENSMUST00000108053.9
    Conserved Domains (2) summary
    pfam00178
    Location:150229
    Ets; Ets-domain
    pfam12310
    Location:2048
    Elf-1_N; Transcription factor protein N terminal
  4. NM_001356358.1NP_001343287.1  ETS-related transcription factor Elf-2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC118601, AC161183
    Conserved Domains (2) summary
    pfam00178
    Location:118198
    Ets; Ets-domain
    pfam12310
    Location:229
    Elf-1_N; Transcription factor protein N terminal
  5. NM_023502.2NP_075991.1  ETS-related transcription factor Elf-2 isoform 1

    See identical proteins and their annotated locations for NP_075991.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC118601, AC161183, AF256217
    Consensus CDS
    CCDS17337.1
    UniProtKB/Swiss-Prot
    Q9JHC9
    Related
    ENSMUSP00000141197.2, ENSMUST00000194641.6
    Conserved Domains (2) summary
    pfam00178
    Location:209289
    Ets; Ets-domain
    pfam12310
    Location:3108
    Elf-1_N; Transcription factor protein N terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    51160141..51248101 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319714.3XP_017175203.1  ETS-related transcription factor Elf-2 isoform X5

    Conserved Domains (1) summary
    pfam00178
    Location:105185
    Ets; Ets-domain
  2. XM_036163288.1XP_036019181.1  ETS-related transcription factor Elf-2 isoform X2

    Conserved Domains (2) summary
    pfam00178
    Location:197277
    Ets; Ets-domain
    pfam12310
    Location:3108
    Elf-1_N; Transcription factor protein N terminal
  3. XM_030252804.1XP_030108664.1  ETS-related transcription factor Elf-2 isoform X6

    Conserved Domains (1) summary
    pfam00178
    Location:94173
    Ets; Ets-domain
  4. XM_036163287.1XP_036019180.1  ETS-related transcription factor Elf-2 isoform X1

    Related
    ENSMUSP00000126871.2, ENSMUST00000163748.8
    Conserved Domains (2) summary
    pfam00178
    Location:209289
    Ets; Ets-domain
    pfam12310
    Location:3108
    Elf-1_N; Transcription factor protein N terminal
  5. XM_030252807.1XP_030108667.1  ETS-related transcription factor Elf-2 isoform X7

    Conserved Domains (1) summary
    pfam00178
    Location:74154
    Ets; Ets-domain
  6. XM_006502031.4XP_006502094.1  ETS-related transcription factor Elf-2 isoform X3

    See identical proteins and their annotated locations for XP_006502094.1

    Conserved Domains (2) summary
    pfam00178
    Location:130210
    Ets; Ets-domain
    pfam12310
    Location:229
    Elf-1_N; Transcription factor protein N terminal
  7. XM_036163295.1XP_036019188.1  ETS-related transcription factor Elf-2 isoform X7

    Conserved Domains (1) summary
    pfam00178
    Location:74154
    Ets; Ets-domain
  8. XM_036163291.1XP_036019184.1  ETS-related transcription factor Elf-2 isoform X4

    Conserved Domains (2) summary
    pfam00178
    Location:118198
    Ets; Ets-domain
    pfam12310
    Location:229
    Elf-1_N; Transcription factor protein N terminal
  9. XM_036163289.1XP_036019182.1  ETS-related transcription factor Elf-2 isoform X3

    Conserved Domains (2) summary
    pfam00178
    Location:130210
    Ets; Ets-domain
    pfam12310
    Location:229
    Elf-1_N; Transcription factor protein N terminal
  10. XM_036163290.1XP_036019183.1  ETS-related transcription factor Elf-2 isoform X3

    Conserved Domains (2) summary
    pfam00178
    Location:130210
    Ets; Ets-domain
    pfam12310
    Location:229
    Elf-1_N; Transcription factor protein N terminal
  11. XM_036163292.1XP_036019185.1  ETS-related transcription factor Elf-2 isoform X5

    Conserved Domains (1) summary
    pfam00178
    Location:105185
    Ets; Ets-domain
  12. XM_030252805.1XP_030108665.1  ETS-related transcription factor Elf-2 isoform X6

    Conserved Domains (1) summary
    pfam00178
    Location:94173
    Ets; Ets-domain
  13. XM_036163293.1XP_036019186.1  ETS-related transcription factor Elf-2 isoform X5

    Conserved Domains (1) summary
    pfam00178
    Location:105185
    Ets; Ets-domain
  14. XM_030252806.1XP_030108666.1  ETS-related transcription factor Elf-2 isoform X7

    Conserved Domains (1) summary
    pfam00178
    Location:74154
    Ets; Ets-domain
  15. XM_006502034.5XP_006502097.1  ETS-related transcription factor Elf-2 isoform X7

    See identical proteins and their annotated locations for XP_006502097.1

    Conserved Domains (1) summary
    pfam00178
    Location:74154
    Ets; Ets-domain
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