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Tmem97 transmembrane protein 97 [ Mus musculus (house mouse) ]

Gene ID: 69071, updated on 8-May-2024

Summary

Official Symbol
Tmem97provided by MGI
Official Full Name
transmembrane protein 97provided by MGI
Primary source
MGI:MGI:1916321
See related
Ensembl:ENSMUSG00000037278 AllianceGenome:MGI:1916321
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D11Bhm182e; 1810014L12Rik
Summary
Predicted to be involved in cholesterol homeostasis. Predicted to be located in several cellular components, including lysosome; nuclear membrane; and rough endoplasmic reticulum. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; limb; male reproductive gland or organ; and skeleton. Orthologous to human TMEM97 (transmembrane protein 97). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 206.9), liver E18 (RPKM 37.6) and 15 other tissues See more
Orthologs
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Genomic context

See Tmem97 in Genome Data Viewer
Location:
11 B5; 11 46.74 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (78432643..78441561, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78541817..78550735, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene tumor necrosis factor, alpha-induced protein 1 (endothelial) Neighboring gene intraflagellar transport 20 Neighboring gene STARR-positive B cell enhancer ABC_E3979 Neighboring gene ribosomal protein L10 pseudogene Neighboring gene predicted gene, 22947

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3)  1 citation
  • Targeted (2) 

General gene information

Markers

Clone Names

  • MGC102369

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables oxysterol binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in rough endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sigma intracellular receptor 2
Names
sigma-2 receptor
sigma2 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133706.2NP_598467.1  sigma intracellular receptor 2

    See identical proteins and their annotated locations for NP_598467.1

    Status: PROVISIONAL

    Source sequence(s)
    AL591177
    Consensus CDS
    CCDS25112.1
    UniProtKB/Swiss-Prot
    Q8VD00
    Related
    ENSMUSP00000099532.5, ENSMUST00000103242.5
    Conserved Domains (1) summary
    pfam10914
    Location:11150
    DUF2781; Protein of unknown function (DUF2781)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    78432643..78441561 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)