U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ebpl emopamil binding protein-like [ Mus musculus (house mouse) ]

Gene ID: 68177, updated on 5-Mar-2024

Summary

Official Symbol
Ebplprovided by MGI
Official Full Name
emopamil binding protein-likeprovided by MGI
Primary source
MGI:MGI:1915427
See related
Ensembl:ENSMUSG00000021928 AllianceGenome:MGI:1915427
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EBRP; 5730442K12Rik
Summary
Predicted to enable cholestenol delta-isomerase activity. Predicted to be involved in sterol metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in central nervous system; retina; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human EBPL (EBP like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver adult (RPKM 31.5), bladder adult (RPKM 12.5) and 26 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ebpl in Genome Data Viewer
Location:
14 D1; 14 32.72 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (61577212..61597894, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (61339763..61360445, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 11 Neighboring gene predicted gene 5461 Neighboring gene predicted gene, 25716 Neighboring gene STARR-positive B cell enhancer ABC_E8563 Neighboring gene karyopherin subunit alpha 3 Neighboring gene STARR-positive B cell enhancer ABC_E1898 Neighboring gene ribosomal protein S12, pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cholestenol delta-isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in sterol metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
emopamil-binding protein-like
Names
emopamil binding related protein, delta8-delta7 sterol isomerase related protein
emopamil-binding-related protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026598.3NP_080874.2  emopamil-binding protein-like

    See identical proteins and their annotated locations for NP_080874.2

    Status: VALIDATED

    Source sequence(s)
    AC154435, AK019963, BY349880
    Consensus CDS
    CCDS27183.1
    UniProtKB/Swiss-Prot
    Q3TQR1, Q9CRQ2, Q9CY81, Q9D0P0
    Related
    ENSMUSP00000022494.9, ENSMUST00000022494.10
    Conserved Domains (1) summary
    pfam05241
    Location:24193
    EBP; Emopamil binding protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    61577212..61597894 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)