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Cfap298 cilia and flagella associate protien 298 [ Mus musculus (house mouse) ]

Gene ID: 68001, updated on 26-Sep-2022


Official Symbol
Cfap298provided by MGI
Official Full Name
cilia and flagella associate protien 298provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000022972 AllianceGenome:MGI:1915251
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to be involved in cilium assembly and regulation of cilium movement. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 26. Orthologous to human CFAP298 (cilia and flagella associated protein 298). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in testis adult (RPKM 38.1), CNS E11.5 (RPKM 13.4) and 28 other tissues See more
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Genomic context

See Cfap298 in Genome Data Viewer
16; 16 C3.3
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (90721178..90731737, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (90925811..90934849, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene URB1 ribosome biogenesis 1 homolog (S. cerevisiae) Neighboring gene eva-1 homolog C (C. elegans) Neighboring gene predicted gene, 36363 Neighboring gene predicted gene, 53919 Neighboring gene synaptojanin 1 Neighboring gene RIKEN cDNA 4930404I05 gene Neighboring gene PAX3 and PAX7 binding protein 1

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
Process Evidence Code Pubs
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
involved_in regulation of cilium movement ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
located_in cilium IEA
Inferred from Electronic Annotation
more info
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
located_in cytosol ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
cilia- and flagella-associated protein 298
UPF0769 protein C21orf59 homolog
protein kurly homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026502.2NP_080778.2  cilia- and flagella-associated protein 298

    See identical proteins and their annotated locations for NP_080778.2

    Status: VALIDATED

    Source sequence(s)
    AK045905, CX236612
    Consensus CDS
    Q8BL95, Q8VCL7
    ENSMUSP00000023694.4, ENSMUST00000023694.11
    Conserved Domains (1) summary
    DUF2870; Protein of unknown function (DUF2870)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000082.7 Reference GRCm39 C57BL/6J

    90721178..90731737 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160103.1XP_036015996.1  cilia- and flagella-associated protein 298 isoform X1

    Conserved Domains (1) summary
    DUF2870; Protein of unknown function (DUF2870)