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Ilf2 interleukin enhancer binding factor 2 [ Mus musculus (house mouse) ]

Gene ID: 67781, updated on 9-May-2024

Summary

Official Symbol
Ilf2provided by MGI
Official Full Name
interleukin enhancer binding factor 2provided by MGI
Primary source
MGI:MGI:1915031
See related
Ensembl:ENSMUSG00000001016 AllianceGenome:MGI:1915031
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tex261; Tex267; TEG-267; 6230405A16Rik
Summary
Predicted to enable DNA binding activity and double-stranded RNA binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Located in nucleolus. Is expressed in several structures, including brain; early conceptus; ganglia; gonad; and incisor. Orthologous to human ILF2 (interleukin enhancer binding factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 75.1), CNS E14 (RPKM 54.2) and 22 other tissues See more
Orthologs
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Genomic context

See Ilf2 in Genome Data Viewer
Location:
3 F1; 3 39.23 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (90383421..90395686)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (90476201..90488379)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene natriuretic peptide receptor 1 Neighboring gene STARR-positive B cell enhancer ABC_E6072 Neighboring gene STARR-positive B cell enhancer ABC_E56 Neighboring gene nuclear encoded tRNA methionine 11 (anticodon CAT) Neighboring gene STARR-positive B cell enhancer ABC_E2084 Neighboring gene SNAP-associated protein Neighboring gene chromatin target of PRMT1 Neighboring gene STARR-positive B cell enhancer ABC_E2085 Neighboring gene STARR-seq mESC enhancer starr_08290 Neighboring gene S100 calcium binding protein A1 Neighboring gene S100 calcium binding protein A13

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables double-stranded RNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
interleukin enhancer-binding factor 2
Names
nuclear factor of activated T-cells 45 kDa
testis expressed gene 267

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026374.3NP_080650.1  interleukin enhancer-binding factor 2

    See identical proteins and their annotated locations for NP_080650.1

    Status: PROVISIONAL

    Source sequence(s)
    AC160552
    Consensus CDS
    CCDS17530.1
    UniProtKB/Swiss-Prot
    Q3U083, Q5RKG0, Q8CCY9, Q99KS3, Q9CXY6
    UniProtKB/TrEMBL
    Q3UXI9
    Related
    ENSMUSP00000001042.9, ENSMUST00000001042.10
    Conserved Domains (1) summary
    smart00572
    Location:98338
    DZF; domain in DSRM or ZnF_C2H2 domain containing proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    90383421..90395686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163253.1XP_036019146.1  interleukin enhancer-binding factor 2 isoform X1

    Conserved Domains (1) summary
    cl02675
    Location:1182
    DZF; DZF domain