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Gpatch2 G patch domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 67769, updated on 2-Nov-2024

Summary

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Official Symbol
Gpatch2provided by MGI
Official Full Name
G patch domain containing 2provided by MGI
Primary source
MGI:MGI:1915019
See related
Ensembl:ENSMUSG00000039210 AllianceGenome:MGI:1915019
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gpatc2; 5830433G22Rik; 5830436K05Rik
Summary
Predicted to enable nucleic acid binding activity. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Orthologous to human GPATCH2 (G-patch domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 4.4), CNS E11.5 (RPKM 2.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Gpatch2 in Genome Data Viewer
Location:
1; 1 H5
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (186946855..187103839)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (187214606..187371645)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 17 Neighboring gene RIKEN cDNA 1700007P06 gene Neighboring gene STARR-seq mESC enhancer starr_03364 Neighboring gene predicted gene 15509 Neighboring gene STARR-seq mESC enhancer starr_03365 Neighboring gene STARR-positive B cell enhancer ABC_E2596 Neighboring gene predicted gene, 51737 Neighboring gene STARR-positive B cell enhancer mm9_chr1:189146346-189146647 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:189172430-189172617 Neighboring gene STARR-seq mESC enhancer starr_03368 Neighboring gene STARR-positive B cell enhancer ABC_E8782 Neighboring gene predicted gene, 37896 Neighboring gene predicted gene, 36249

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Deletion of Gpatch2 does not alter Tnf expression in mice. Dalseno D, et al. Cell Death Dis, 2023 Mar 27. PMID 36973252, Free PMC Article
  2. A global genomic transcriptional code associated with CNS-expressed genes. Bailey PJ, et al. Exp Cell Res, 2006 Oct 1. PMID 16919269
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Deletion of Gpatch2 does not alter Tnf expression in mice.
    Title: Deletion of Gpatch2 does not alter Tnf expression in mice.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
G patch domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357645.1 → NP_001344574.1  G patch domain-containing protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC107843, AC108796
    Consensus CDS
    CCDS87942.1
    Related
    ENSMUSP00000124407.2, ENSMUST00000160471.8
    Conserved Domains (1) summary
    pfam01585
    Location:444 → 485
    G-patch; G-patch domain

  2. NM_001357646.1 → NP_001344575.1  G patch domain-containing protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC107843, AC108796
    Consensus CDS
    CCDS87941.1
    Related
    ENSMUSP00000106568.3, ENSMUST00000110943.9
    Conserved Domains (1) summary
    pfam01585
    Location:429 → 471
    G-patch; G-patch domain

  3. NM_001357647.1 → NP_001344576.1  G patch domain-containing protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC107843
    UniProtKB/TrEMBL
    Q3TIJ8

  4. NM_001357648.1 → NP_001344577.1  G patch domain-containing protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC107843
    Consensus CDS
    CCDS87940.1
    UniProtKB/TrEMBL
    E9PY25, Q9D3E7
    Related
    ENSMUSP00000048979.6, ENSMUST00000044812.12

  5. NM_026367.4 → NP_080643.4  G patch domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_080643.4

    Status: VALIDATED

    Source sequence(s)
    AC107843, AC108796
    Consensus CDS
    CCDS15605.1
    UniProtKB/Swiss-Prot
    Q7TQC7, Q8BNJ9, Q8BPM1, Q8CDH9
    Related
    ENSMUSP00000065009.8, ENSMUST00000065573.14
    Conserved Domains (1) summary
    pfam01585
    Location:467 → 510
    G-patch; G-patch domain

RNA

  1. NR_151741.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC107843, AC108796

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    186946855..187103839
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242477.2 → XP_030098337.1  G patch domain-containing protein 2 isoform X1

    Conserved Domains (1) summary
    pfam01585
    Location:444 → 485
    G-patch; G-patch domain

  2. XM_030242487.1 → XP_030098347.1  G patch domain-containing protein 2 isoform X5

    Conserved Domains (1) summary
    pfam01585
    Location:216 → 257
    G-patch; G-patch domain

  3. XM_006497199.5 → XP_006497262.1  G patch domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    M0QWF5

  4. XM_006497198.4 → XP_006497261.1  G patch domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    M0QWF5

  5. XM_036153167.1 → XP_036009060.1  G patch domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    M0QWF5
    Related
    ENSMUSP00000137801.2, ENSMUST00000160481.8

  6. XM_030242485.1 → XP_030098345.1  G patch domain-containing protein 2 isoform X5

    Conserved Domains (1) summary
    pfam01585
    Location:216 → 257
    G-patch; G-patch domain

RNA

  1. XR_003946457.2 RNA Sequence

  2. XR_004934119.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7TQC7.2 GenPept UniProtKB/Swiss-Prot:Q7TQC7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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