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Cog6 component of oligomeric golgi complex 6 [ Mus musculus (house mouse) ]

Gene ID: 67542, updated on 9-May-2024

Summary

Official Symbol
Cog6provided by MGI
Official Full Name
component of oligomeric golgi complex 6provided by MGI
Primary source
MGI:MGI:1914792
See related
Ensembl:ENSMUSG00000027742 AllianceGenome:MGI:1914792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1134; 4933405E16Rik
Summary
Predicted to be involved in glycosylation and intra-Golgi vesicle-mediated transport. Predicted to act upstream of or within protein transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be part of Golgi transport complex. Is expressed in retina outer nuclear layer. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Orthologous to human COG6 (component of oligomeric golgi complex 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 39.3), heart adult (RPKM 17.2) and 28 other tissues See more
Orthologs
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Genomic context

See Cog6 in Genome Data Viewer
Location:
3 C; 3 24.1 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (52889544..52924644, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (52982123..53017223, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30351 Neighboring gene STARR-positive B cell enhancer ABC_E2070 Neighboring gene predicted gene, 30402 Neighboring gene LHFPL tetraspan subfamily member 6 Neighboring gene STARR-seq mESC enhancer starr_07650 Neighboring gene STARR-seq mESC enhancer starr_07651 Neighboring gene STARR-seq mESC enhancer starr_07652 Neighboring gene STARR-seq mESC enhancer starr_07654 Neighboring gene predicted gene, 40048

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
 
involved_in glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde transport, vesicle recycling within Golgi ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
part_of Golgi transport complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Golgi transport complex ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
conserved oligomeric Golgi complex subunit 6
Names
COG complex subunit 6
conserved oligomeric Golgi complex protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026225.3NP_080501.2  conserved oligomeric Golgi complex subunit 6

    See identical proteins and their annotated locations for NP_080501.2

    Status: VALIDATED

    Source sequence(s)
    AK016663, AK153320
    Consensus CDS
    CCDS50905.1
    UniProtKB/Swiss-Prot
    Q8BSN7, Q8CHB1, Q8R3I3, Q9CTA8
    UniProtKB/TrEMBL
    A0A0R4J0L5
    Related
    ENSMUSP00000048603.5, ENSMUST00000036665.10
    Conserved Domains (1) summary
    pfam06419
    Location:56652
    COG6; Conserved oligomeric complex COG6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    52889544..52924644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)