U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pigc phosphatidylinositol glycan anchor biosynthesis, class C [ Mus musculus (house mouse) ]

Gene ID: 67292, updated on 18-Sep-2024

Summary

Official Symbol
Pigcprovided by MGI
Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class Cprovided by MGI
Primary source
MGI:MGI:1914542
See related
Ensembl:ENSMUSG00000026698 AllianceGenome:MGI:1914542
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110030E07Rik
Summary
Predicted to enable phosphatidylinositol N-acetylglucosaminyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be part of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex. Is expressed in eye; facial bone primordium; and nervous system. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human PIGC (phosphatidylinositol glycan anchor biosynthesis class C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 10.1), limb E14.5 (RPKM 9.0) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Pigc in Genome Data Viewer
Location:
1 H2.1; 1 69.95 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (161796757..161801029)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (161969188..161973460)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10050 Neighboring gene cyclin-dependent kinase 7 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2578 Neighboring gene SUN domain containing ossification factor Neighboring gene STARR-positive B cell enhancer ABC_E7766 Neighboring gene STARR-seq mESC enhancer starr_02830 Neighboring gene RIKEN cDNA 4930558K02 gene Neighboring gene predicted gene, 31925 Neighboring gene STARR-positive B cell enhancer ABC_E4367 Neighboring gene STARR-positive B cell enhancer mm9_chr1:163906574-163906875 Neighboring gene STARR-seq mESC enhancer starr_02833 Neighboring gene RIKEN cDNA 2810442N19 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:163930050-163930233 Neighboring gene dynamin 3 Neighboring gene STARR-seq mESC enhancer starr_02834 Neighboring gene VISTA enhancer mm712 Neighboring gene STARR-seq mESC enhancer starr_02835 Neighboring gene STARR-seq mESC enhancer starr_02836 Neighboring gene microRNA 199a-2 Neighboring gene dynamin 3, opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
phosphatidylinositol N-acetylglucosaminyltransferase subunit C
Names
PIG-C
phosphatidylinositol-glycan biosynthesis class C protein
NP_001034134.1
NP_080354.1
XP_006497022.1
XP_030098184.1
XP_036009010.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039045.1NP_001034134.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit C

    See identical proteins and their annotated locations for NP_001034134.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK152660, CAAA01056494, CJ171161
    Consensus CDS
    CCDS15419.1
    UniProtKB/Swiss-Prot
    Q3U7H3, Q9CXR4
    UniProtKB/TrEMBL
    Q3TDK1, Q3U1G9
    Related
    ENSMUSP00000107221.3, ENSMUST00000111594.3
    Conserved Domains (1) summary
    pfam06432
    Location:14284
    GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase
  2. NM_026078.2NP_080354.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit C

    See identical proteins and their annotated locations for NP_080354.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK014096, CAAA01056494, CJ171161
    Consensus CDS
    CCDS15419.1
    UniProtKB/Swiss-Prot
    Q3U7H3, Q9CXR4
    UniProtKB/TrEMBL
    Q3TDK1, Q3U1G9
    Related
    ENSMUSP00000028021.7, ENSMUST00000028021.7
    Conserved Domains (1) summary
    pfam06432
    Location:14284
    GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    161796757..161801029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496959.3XP_006497022.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit C isoform X1

    See identical proteins and their annotated locations for XP_006497022.1

    UniProtKB/Swiss-Prot
    Q3U7H3, Q9CXR4
    UniProtKB/TrEMBL
    Q3TDK1, Q3U1G9
    Conserved Domains (1) summary
    pfam06432
    Location:14284
    GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase
  2. XM_030242324.2XP_030098184.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit C isoform X1

    UniProtKB/Swiss-Prot
    Q3U7H3, Q9CXR4
    UniProtKB/TrEMBL
    Q3TDK1, Q3U1G9
    Conserved Domains (1) summary
    pfam06432
    Location:14284
    GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase
  3. XM_036153117.1XP_036009010.1  phosphatidylinositol N-acetylglucosaminyltransferase subunit C isoform X1

    UniProtKB/Swiss-Prot
    Q3U7H3, Q9CXR4
    UniProtKB/TrEMBL
    Q3TDK1, Q3U1G9
    Related
    ENSMUSP00000141646.2, ENSMUST00000193784.2
    Conserved Domains (1) summary
    pfam06432
    Location:14284
    GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase