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SPRR2A small proline rich protein 2A [ Homo sapiens (human) ]

Gene ID: 6700, updated on 21-Dec-2019

Summary

Official Symbol
SPRR2Aprovided by HGNC
Official Full Name
small proline rich protein 2Aprovided by HGNC
Primary source
HGNC:HGNC:11261
See related
Ensembl:ENSG00000241794 MIM:182267
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward esophagus (RPKM 1789.3) See more

Genomic context

See SPRR2A in Genome Data Viewer
Location:
1q21.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (153056120..153057512, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (153028596..153029988, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene small proline rich protein 1B Neighboring gene small proline rich protein 2D Neighboring gene small proline rich protein 2B Neighboring gene small proline rich protein 2E

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cornification TAS
Traceable Author Statement
more info
 
epidermis development NAS
Non-traceable Author Statement
more info
PubMed 
keratinocyte differentiation NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cornified envelope NAS
Non-traceable Author Statement
more info
PubMed 
cornified envelope TAS
Traceable Author Statement
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
small proline-rich protein 2A
Names
2-1
SPR-2A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005988.3NP_005979.1  small proline-rich protein 2A

    See identical proteins and their annotated locations for NP_005979.1

    Status: VALIDATED

    Source sequence(s)
    BE710686, CA433267, X53064
    Consensus CDS
    CCDS1034.1
    UniProtKB/Swiss-Prot
    P35326
    Related
    ENSP00000376423.2, ENST00000392653.3

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    153056120..153057512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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