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Pomp proteasome maturation protein [ Mus musculus (house mouse) ]

Gene ID: 66537, updated on 5-Mar-2024

Summary

Official Symbol
Pompprovided by MGI
Official Full Name
proteasome maturation proteinprovided by MGI
Primary source
MGI:MGI:1913787
See related
Ensembl:ENSMUSG00000029649 AllianceGenome:MGI:1913787
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ump1; 2510048O06Rik
Summary
Predicted to be involved in proteasome assembly. Located in cytoplasm and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and thymus primordium. Orthologous to human POMP (proteasome maturation protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 79.0), CNS E11.5 (RPKM 73.2) and 28 other tissues See more
Orthologs
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Genomic context

See Pomp in Genome Data Viewer
Location:
5 G3; 5 87.52 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (147797438..147812594)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (147860628..147875784)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_14882 Neighboring gene predicted gene, 35592 Neighboring gene predicted gene, 54314 Neighboring gene STARR-seq mESC enhancer starr_14883 Neighboring gene predicted gene, 35648 Neighboring gene solute carrier family 46, member 3 Neighboring gene STARR-positive B cell enhancer ABC_E534 Neighboring gene predicted gene, 46943

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in proteasome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteasome assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
proteasome maturation protein
Names
proteassemblin
protein UMP1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025624.3NP_079900.1  proteasome maturation protein

    See identical proteins and their annotated locations for NP_079900.1

    Status: VALIDATED

    Source sequence(s)
    AK011115, AK012455
    Consensus CDS
    CCDS39402.1
    UniProtKB/Swiss-Prot
    Q9CQT5, Q9CXV8, Q9CZL7
    Related
    ENSMUSP00000031654.7, ENSMUST00000031654.10
    Conserved Domains (1) summary
    pfam05348
    Location:25138
    UMP1; Proteasome maturation factor UMP1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    147797438..147812594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)