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Dmac2 distal membrane arm assembly complex 2 [ Mus musculus (house mouse) ]

Gene ID: 66349, updated on 5-Mar-2024

Summary

Official Symbol
Dmac2provided by MGI
Official Full Name
distal membrane arm assembly complex 2provided by MGI
Primary source
MGI:MGI:1913599
See related
Ensembl:ENSMUSG00000057229 AllianceGenome:MGI:1913599
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atp5sl; 2310004L02Rik; C030044E10Rik
Summary
Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Orthologous to human DMAC2 (distal membrane arm assembly component 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in duodenum adult (RPKM 27.8), kidney adult (RPKM 26.0) and 28 other tissues See more
Orthologs
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Genomic context

See Dmac2 in Genome Data Viewer
Location:
7 A3; 7 13.93 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (25318839..25324975)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (25619414..25625550)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L15 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E9286 Neighboring gene glutamate rich 4 Neighboring gene predicted gene, 38969 Neighboring gene predicted gene, 57782 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 Neighboring gene branched chain ketoacid dehydrogenase E1, alpha polypeptide Neighboring gene STARR-positive B cell enhancer ABC_E8156 Neighboring gene STARR-positive B cell enhancer ABC_E10430 Neighboring gene STARR-seq mESC enhancer starr_18309

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General protein information

Preferred Names
distal membrane-arm assembly complex protein 2
Names
ATP synthase subunit s-like protein
ATP5S-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290487.1NP_001277416.1  distal membrane-arm assembly complex protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001277416.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC162614, AK009150
    Consensus CDS
    CCDS71917.1
    UniProtKB/Swiss-Prot
    Q9D7K5
    UniProtKB/TrEMBL
    Q9DCX4
    Related
    ENSMUSP00000076563.6, ENSMUST00000077338.12
    Conserved Domains (2) summary
    cd09293
    Location:149221
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:151176
    LRR_AMN1; leucine-rich repeat [structural motif]
  2. NM_025504.4NP_079780.2  distal membrane-arm assembly complex protein 2 isoform 2

    See identical proteins and their annotated locations for NP_079780.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate first exon compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC162614
    Consensus CDS
    CCDS20988.1
    UniProtKB/TrEMBL
    Q8CA44, Q9DCX4
    Related
    ENSMUSP00000083115.4, ENSMUST00000085953.5
    Conserved Domains (2) summary
    cd09293
    Location:148220
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:150175
    LRR_AMN1; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    25318839..25324975
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)