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Nat8f1 N-acetyltransferase 8 (GCN5-related) family member 1 [ Mus musculus (house mouse) ]

Gene ID: 66116, updated on 8-Feb-2024

Summary

Official Symbol
Nat8f1provided by MGI
Official Full Name
N-acetyltransferase 8 (GCN5-related) family member 1provided by MGI
Primary source
MGI:MGI:1913366
See related
Ensembl:ENSMUSG00000057103 AllianceGenome:MGI:1913366
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cml1; 1110002I11Rik
Summary
Predicted to enable cysteine-S-conjugate N-acetyltransferase activity and lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Predicted to be involved in several processes, including negative regulation of apoptotic process; peptide metabolic process; and peptidyl-lysine N6-acetylation. Predicted to act upstream of or within negative regulation of cell adhesion. Located in mitochondrial inner membrane. Is expressed in urinary system. Orthologous to human NAT8 (N-acetyltransferase 8 (putative)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 284.1), liver adult (RPKM 210.3) and 2 other tissues See more
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Genomic context

See Nat8f1 in Genome Data Viewer
Location:
6 C3; 6 37.53 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (85887136..85893210, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (85910154..85915914, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_16511 Neighboring gene 60S ribosomal protein L23a-like Neighboring gene STARR-seq mESC enhancer starr_16512 Neighboring gene N-acetyltransferase 8 (GCN5-related) family member 4 Neighboring gene STARR-positive B cell enhancer ABC_E11321 Neighboring gene Tp53rk binding protein Neighboring gene syndecan binding protein pseudogene Neighboring gene N-acetyltransferase 8B, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables N-acetyltransferase activity NAS
Non-traceable Author Statement
more info
PubMed 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
 
enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
probable N-acetyltransferase CML1
Names
camello-like 1
camello-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023160.3NP_075649.3  probable N-acetyltransferase CML1

    Status: VALIDATED

    Source sequence(s)
    AC158679, AC161888
    Consensus CDS
    CCDS20304.3
    UniProtKB/Swiss-Prot
    E0CYC6, Q91XE3, Q9CW77, Q9JIZ0
    Related
    ENSMUSP00000124488.4, ENSMUST00000161198.4
    Conserved Domains (1) summary
    pfam13508
    Location:106195
    Acetyltransf_7; Acetyltransferase (GNAT) domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    85887136..85893210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506470.4XP_006506533.1  probable N-acetyltransferase CML1 isoform X1

    See identical proteins and their annotated locations for XP_006506533.1

    UniProtKB/Swiss-Prot
    E0CYC6
    UniProtKB/TrEMBL
    E9PUL7
    Conserved Domains (1) summary
    pfam00583
    Location:101203
    Acetyltransf_1; Acetyltransferase (GNAT) family