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KCTD14 potassium channel tetramerization domain containing 14 [ Homo sapiens (human) ]

Gene ID: 65987, updated on 24-Nov-2020

Summary

Official Symbol
KCTD14provided by HGNC
Official Full Name
potassium channel tetramerization domain containing 14provided by HGNC
Primary source
HGNC:HGNC:23295
See related
Ensembl:ENSG00000151364
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in adrenal (RPKM 10.1), stomach (RPKM 9.5) and 17 other tissues See more
Orthologs

Genomic context

See KCTD14 in Genome Data Viewer
Location:
11q14.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (78015715..78046191, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (77726761..77757237, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene remodeling and spacing factor 1 Neighboring gene adipogenesis associated Mth938 domain containing Neighboring gene ribosomal protein L21 pseudogene 95 Neighboring gene integrator complex subunit 4 Neighboring gene NDUFC2-KCTD14 readthrough Neighboring gene uncharacterized LOC105369401 Neighboring gene NADH:ubiquinone oxidoreductase subunit C2 Neighboring gene thyroid hormone responsive

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough NDUFC2-KCTD14

Readthrough gene: NDUFC2-KCTD14, Included gene: NDUFC2

Homology

Clone Names

  • MGC2376, FLJ94527

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
protein homooligomerization IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BTB/POZ domain-containing protein KCTD14
Names
potassium channel tetramerisation domain containing 14

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001282406.2NP_001269335.1  BTB/POZ domain-containing protein KCTD14 isoform 2

    See identical proteins and their annotated locations for NP_001269335.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate 5' structure that results in use of downstream in-frame AUG compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AK313892, AP003032, BC001929
    Consensus CDS
    CCDS60908.1
    UniProtKB/Swiss-Prot
    Q9BQ13
    Related
    ENSP00000431155.1, ENST00000533144.1
    Conserved Domains (1) summary
    cd18371
    Location:2100
    BTB_POZ_KCTD14; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 14 (KCTD14)
  2. NM_023930.4NP_076419.2  BTB/POZ domain-containing protein KCTD14 isoform 1

    See identical proteins and their annotated locations for NP_076419.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AP003032, BC001929, BU631809, CB993622
    Consensus CDS
    CCDS8255.2
    UniProtKB/Swiss-Prot
    Q9BQ13
    Related
    ENSP00000316482.5, ENST00000353172.6
    Conserved Domains (2) summary
    smart00225
    Location:35125
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cl02518
    Location:35118
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    78015715..78046191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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