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PPIAL4A peptidylprolyl isomerase A like 4A [ Homo sapiens (human) ]

Gene ID: 653505, updated on 11-Jun-2021

Summary

Official Symbol
PPIAL4Aprovided by HGNC
Official Full Name
peptidylprolyl isomerase A like 4Aprovided by HGNC
Primary source
HGNC:HGNC:24369
See related
Ensembl:ENSG00000263353
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
COAS2; COAS-2; PPIAL4; PPIAL4B
Orthologs
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Genomic context

See PPIAL4A in Genome Data Viewer
Location:
1p11.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (120889771..120890530)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (144363587..144364246, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene tRNA-Asn (anticodon GTT) 7-1 Neighboring gene RNA, variant U1 small nuclear 19 Neighboring gene uncharacterized LOC100996720 Neighboring gene long intergenic non-protein coding RNA 623 Neighboring gene RNA, variant U1 small nuclear 4

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC163248, MGC163250, MGC199037

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cyclosporin A binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptidyl-prolyl cis-trans isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein peptidyl-prolyl isomerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular exosome HDA PubMed 
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
peptidyl-prolyl cis-trans isomerase A-like 4A
Names
PPIase A-like 4B
PPIase A-like 4G
chromosome 1-amplified sequence 2
chromosome one-amplified sequence 2
cyclophilin homolog overexpressed in liver cancer
cyclophilin-LC (COAS2)
peptidyl-prolyl cis-trans isomerase A-like 4A/B/C
peptidylprolyl cis-trans isomerase A-like 4B
peptidylprolyl isomerase A (cyclophilin A)-like 4A
peptidylprolyl isomerase A (cyclophilin A)-like 4B
NP_001137355.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143883.4NP_001137355.1  peptidyl-prolyl cis-trans isomerase A-like 4A

    See identical proteins and their annotated locations for NP_001137355.1

    Status: VALIDATED

    Source sequence(s)
    AC253572
    Consensus CDS
    CCDS76197.1
    UniProtKB/Swiss-Prot
    Q9Y536
    Related
    ENSP00000485206.1, ENST00000577856.2
    Conserved Domains (1) summary
    cl00197
    Location:4162
    cyclophilin; cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    120889771..120890530
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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