U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nif3l1 Ngg1 interacting factor 3-like 1 (S. pombe) [ Mus musculus (house mouse) ]

Gene ID: 65102, updated on 5-Mar-2024

Summary

Official Symbol
Nif3l1provided by MGI
Official Full Name
Ngg1 interacting factor 3-like 1 (S. pombe)provided by MGI
Primary source
MGI:MGI:1929485
See related
Ensembl:ENSMUSG00000026036 AllianceGenome:MGI:1929485
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110030G24Rik
Summary
This gene is a member of the NGG1-interacting factor 3-like superfamily of transcriptional regulators and is ubiquitously expressed throughout embryonic development. The encoded protein interacts with a component of the constitutive photomorphogenesis 9 signalosome, and functions as a transcriptional corepressor of genes involved in neuronal differentiation. This gene is highly conserved from bacteria to human. [provided by RefSeq, Sep 2016]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 13.3), CNS E14 (RPKM 12.7) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
1 C1.3; 1 29.1 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (58484310..58501435)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (58445151..58462276)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58450605-58450792 Neighboring gene predicted gene, 53481 Neighboring gene basic leucine zipper and W2 domains 1 Neighboring gene STARR-seq mESC enhancer starr_01013 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58480276-58480459 Neighboring gene STARR-positive B cell enhancer ABC_E5756 Neighboring gene CDC-like kinase 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58501960-58502147 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:58502340-58502523 Neighboring gene peptidylprolyl isomerase (cyclophilin)-like 3 Neighboring gene predicted gene, 23966 Neighboring gene origin recognition complex, subunit 2 Neighboring gene STARR-seq mESC enhancer starr_01014 Neighboring gene STARR-positive B cell enhancer ABC_E3277 Neighboring gene STARR-seq mESC enhancer starr_01015 Neighboring gene predicted gene 15834 Neighboring gene hyccin PI4KA lipid kinase complex subunit 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC107114

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
NIF3-like protein 1
Names
GTP cyclohydrolase I
Ngg1 interacting factor 3 homolog-like 1
putative GTP cyclohydrolase 1 type 2 Nif3l1
NP_075364.2
XP_006496249.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022988.3NP_075364.2  NIF3-like protein 1

    See identical proteins and their annotated locations for NP_075364.2

    Status: REVIEWED

    Source sequence(s)
    AC118698, AK158616, BC065163
    Consensus CDS
    CCDS14973.1
    UniProtKB/Swiss-Prot
    Q6P1B7, Q9D098, Q9EQ80
    UniProtKB/TrEMBL
    Q3V2R8
    Related
    ENSMUSP00000084799.7, ENSMUST00000087521.13
    Conserved Domains (1) summary
    pfam01784
    Location:32353
    NIF3; NIF3 (NGG1p interacting factor 3)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    58484310..58501435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496186.2XP_006496249.1  NIF3-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006496249.1

    UniProtKB/Swiss-Prot
    Q6P1B7, Q9D098, Q9EQ80
    UniProtKB/TrEMBL
    Q3V2R8
    Conserved Domains (1) summary
    pfam01784
    Location:32353
    NIF3; NIF3 (NGG1p interacting factor 3)