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LRRC19 leucine rich repeat containing 19 [ Homo sapiens (human) ]

Gene ID: 64922, updated on 20-Apr-2017
Official Symbol
LRRC19provided by HGNC
Official Full Name
leucine rich repeat containing 19provided by HGNC
Primary source
HGNC:HGNC:23379
See related
Ensembl:ENSG00000184434 Vega:OTTHUMG00000019710
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
Location:
9p21.2
Exon count:
5
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 9 NC_000009.12 (26993136..27005693, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (26993134..27005691, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene phospholipase A2 activating protein Neighboring gene IFT74 antisense RNA 1 Neighboring gene intraflagellar transport 74 Neighboring gene TEK receptor tyrosine kinase Neighboring gene RNA, 5S ribosomal pseudogene 280 Neighboring gene ribosomal protein L36a pseudogene 34

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Markers

Homology

Clone Names

  • FLJ21302

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
cytokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of JAK-STAT cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
leucine-rich repeat-containing protein 19

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022901.2NP_075052.1  leucine-rich repeat-containing protein 19 precursor

    See identical proteins and their annotated locations for NP_075052.1

    Status: VALIDATED

    Source sequence(s)
    AK024955, AK025070, AL355432, BC056252, BC126156, BF431646
    Consensus CDS
    CCDS6518.1
    UniProtKB/Swiss-Prot
    Q9H756
    Related
    ENSP00000369395.5, OTTHUMP00000021165, ENST00000380055.5, OTTHUMT00000051961
    Conserved Domains (4) summary
    sd00031
    Location:4971
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:97157
    LRR_8; Leucine rich repeat
    pfam15176
    Location:257370
    LRR19-TM; Leucine-rich repeat family 19 TM domain
    cl15307
    Location:176227
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p7 Primary Assembly

    Range
    26993136..27005693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018920.2 Alternate CHM1_1.1

    Range
    26992884..27005482 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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