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ZAR1L zygote arrest 1 like [ Homo sapiens (human) ]

Gene ID: 646799, updated on 5-Aug-2022

Summary

Official Symbol
ZAR1Lprovided by HGNC
Official Full Name
zygote arrest 1 likeprovided by HGNC
Primary source
HGNC:HGNC:37116
See related
Ensembl:ENSG00000189167 AllianceGenome:HGNC:37116
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZAR2; Z3CXXC7
Summary
This gene encodes a member of the ZAR1 family that is predominantly expressed in oocytes and early embryos. The protein may function as an RNA regulator in early embryos. [provided by RefSeq, Apr 2010]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See ZAR1L in Genome Data Viewer
Location:
13q13.1
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (32303699..32315363, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (31520944..31532608, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (32877836..32889500, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 10155 Neighboring gene FRY antisense RNA 1 Neighboring gene FRY microtubule binding protein Neighboring gene BRCA2 promoter/silencer region Neighboring gene BRCA2 DNA repair associated Neighboring gene Sharpr-MPRA regulatory region 1962 Neighboring gene interferon induced protein with tetratricopeptide repeats 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ZAR1-like protein
Names
zinc finger, 3CxxC-type 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_017006.2 RefSeqGene

    Range
    5001..16665
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001136571.2NP_001130043.1  ZAR1-like protein

    See identical proteins and their annotated locations for NP_001130043.1

    Status: REVIEWED

    Source sequence(s)
    AL445212, BC146956, DB457084, DB522524
    Consensus CDS
    CCDS45023.1
    UniProtKB/Swiss-Prot
    A6NP61, B7ZBU2
    Related
    ENSP00000437289.2, ENST00000533490.7
    Conserved Domains (1) summary
    pfam13695
    Location:224306
    zf-3CxxC; Zinc-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    32303699..32315363 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    31520944..31532608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)