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Mrps22 mitochondrial ribosomal protein S22 [ Mus musculus (house mouse) ]

Gene ID: 64655, updated on 12-May-2024

Summary

Official Symbol
Mrps22provided by MGI
Official Full Name
mitochondrial ribosomal protein S22provided by MGI
Primary source
MGI:MGI:1928137
See related
Ensembl:ENSMUSG00000032459 AllianceGenome:MGI:1928137
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpms22; 3100002P07Rik
Summary
Predicted to be a structural constituent of ribosome. Located in mitochondrion. Is expressed in several structures, including central nervous system; early conceptus; reproductive system; retina; and spleen. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 5 and ovarian dysgenesis 7. Orthologous to human MRPS22 (mitochondrial ribosomal protein S22). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 24.3), placenta adult (RPKM 17.9) and 28 other tissues See more
Orthologs
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Genomic context

See Mrps22 in Genome Data Viewer
Location:
9 E3.3; 9 51.41 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (98470783..98483732, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (98588730..98601679, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930579K19 gene Neighboring gene STARR-positive B cell enhancer ABC_E3853 Neighboring gene COPI coat complex subunit beta 2 Neighboring gene STARR-seq mESC enhancer starr_25005 Neighboring gene RIKEN cDNA E330023G01 gene Neighboring gene STARR-seq mESC enhancer starr_25007 Neighboring gene predicted gene, 39411 Neighboring gene predicted gene, 33563

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
PubMed 
part_of mitochondrial small ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small ribosomal subunit protein mS22
Names
28S ribosomal protein S22, mitochondrial
MRP-S22
S22mt
ribosomal protein, mitochondrial, S22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025485.3NP_079761.1  small ribosomal subunit protein mS22

    See identical proteins and their annotated locations for NP_079761.1

    Status: VALIDATED

    Source sequence(s)
    AK154600, BE983156, CJ183743
    Consensus CDS
    CCDS23427.1
    UniProtKB/Swiss-Prot
    Q3U3T2, Q8VDG9, Q9CXW2, Q9D185
    Related
    ENSMUSP00000035034.9, ENSMUST00000035034.10
    Conserved Domains (1) summary
    pfam10245
    Location:67307
    MRP-S22; Mitochondrial 28S ribosomal protein S22

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    98470783..98483732 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)