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PABPC1L2B poly(A) binding protein cytoplasmic 1 like 2B [ Homo sapiens (human) ]

Gene ID: 645974, updated on 10-Dec-2024

Summary

Official Symbol
PABPC1L2Bprovided by HGNC
Official Full Name
poly(A) binding protein cytoplasmic 1 like 2Bprovided by HGNC
Primary source
HGNC:HGNC:31852
See related
Ensembl:ENSG00000184388 AllianceGenome:HGNC:31852
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RBM32B
Summary
Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See PABPC1L2B in Genome Data Viewer
Location:
Xq13.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (73002939..73006106)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (71436440..71439607)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (72222778..72225945)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene DMRT like family C1 Neighboring gene family with sequence similarity 226 member A Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:72179367-72179868 Neighboring gene PABPC1L2B antisense RNA 1 (head to head) Neighboring gene ReSE screen-validated silencer GRCh37_chrX:72288168-72288379 Neighboring gene uncharacterized LOC101928380 Neighboring gene poly(A) binding protein cytoplasmic 1 like 2A

Genomic regions, transcripts, and products

General gene information

Markers

Clone Names

  • MGC168104

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables poly(U) RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular exosome HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
polyadenylate-binding protein 1-like 2
Names
RNA binding motif protein 32B
RNA-binding motif protein 32
RNA-binding protein 32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042506.2NP_001035971.1  polyadenylate-binding protein 1-like 2

    See identical proteins and their annotated locations for NP_001035971.1

    Status: VALIDATED

    Source sequence(s)
    AC234776
    Consensus CDS
    CCDS43972.1
    UniProtKB/Swiss-Prot
    B2RMV9, Q5JQF8, Q8IVU8
    Related
    ENSP00000362621.3, ENST00000373521.4
    Conserved Domains (1) summary
    TIGR01628
    Location:2196
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    73002939..73006106
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    71436440..71439607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)