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TSPY2 testis specific protein Y-linked 2 [ Homo sapiens (human) ]

Gene ID: 64591, updated on 11-Jun-2021

Summary

Official Symbol
TSPY2provided by HGNC
Official Full Name
testis specific protein Y-linked 2provided by HGNC
Primary source
HGNC:HGNC:23924
See related
Ensembl:ENSG00000168757
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TSPYQ1
Expression
Restricted expression toward testis (RPKM 29.2) See more
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Genomic context

See TSPY2 in Genome Data Viewer
Location:
Yp11.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) Y NC_000024.10 (6246223..6249020)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (6114264..6117054)

Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene DLGAP5 pseudogene 1 Neighboring gene testis-specific transcript, Y-linked 23B Neighboring gene family with sequence similarity 197 Y-linked member 9 Neighboring gene testis specific protein Y-linked 11, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC103998

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in gonadal mesoderm development IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleosome assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
testis-specific Y-encoded protein 2
Names
testis-specific Y-encoded protein Q1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022573.4NP_072095.2  testis-specific Y-encoded protein 2

    See identical proteins and their annotated locations for NP_072095.2

    Status: VALIDATED

    Source sequence(s)
    AC006335
    Consensus CDS
    CCDS35465.1
    UniProtKB/Swiss-Prot
    A6NKD2
    Related
    ENSP00000314077.4, ENST00000320701.8
    Conserved Domains (1) summary
    cl08298
    Location:126288
    NAP; Nucleosome assembly protein (NAP)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000024.10 Reference GRCh38.p13 Primary Assembly

    Range
    6246223..6249020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005262569.4XP_005262626.1  testis-specific Y-encoded protein 2 isoform X1

    UniProtKB/TrEMBL
    A6NGT6
    Related
    ENSP00000372512.1, ENST00000383042.1
    Conserved Domains (1) summary
    cl08298
    Location:103273
    NAP; Nucleosome assembly protein (NAP)
  2. XM_017030062.1XP_016885551.1  testis-specific Y-encoded protein 2 isoform X2

RNA

  1. XR_001756004.1 RNA Sequence

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