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CPSF4L cleavage and polyadenylation specific factor 4 like [ Homo sapiens (human) ]

Gene ID: 642843, updated on 1-Jun-2020

Summary

Official Symbol
CPSF4Lprovided by HGNC
Official Full Name
cleavage and polyadenylation specific factor 4 likeprovided by HGNC
Primary source
HGNC:HGNC:33632
See related
Ensembl:ENSG00000187959
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in fat (RPKM 2.8), duodenum (RPKM 2.5) and 25 other tissues See more
Orthologs

Genomic context

See CPSF4L in Genome Data Viewer
Location:
17q25.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (73242343..73263778, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (71244588..71258019, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene somatostatin receptor 2 Neighboring gene family with sequence similarity 104 member A Neighboring gene component of oligomeric golgi complex 1 Neighboring gene chromosome 17 open reading frame 80 Neighboring gene Sharpr-MPRA regulatory region 4436 Neighboring gene CDC42 effector protein 4 Neighboring gene sidekick cell adhesion molecule 2 Neighboring gene uncharacterized LOC101928251

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
pre-mRNA cleavage required for polyadenylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
mRNA cleavage and polyadenylation specificity factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
putative cleavage and polyadenylation specificity factor subunit 4-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001129885.1NP_001123357.1  putative cleavage and polyadenylation specificity factor subunit 4-like protein

    See identical proteins and their annotated locations for NP_001123357.1

    Status: VALIDATED

    Source sequence(s)
    BC157870
    Consensus CDS
    CCDS45768.1
    UniProtKB/Swiss-Prot
    A6NMK7
    Related
    ENSP00000343900.4, ENST00000344935.8
    Conserved Domains (1) summary
    COG5084
    Location:12160
    YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    73242343..73263778 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011525115.2XP_011523417.1  putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X1

    Conserved Domains (2) summary
    smart00356
    Location:85108
    ZnF_C3H1; zinc finger
    COG5084
    Location:34182
    YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]
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