U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MANBAL mannosidase beta like [ Homo sapiens (human) ]

Gene ID: 63905, updated on 1-Mar-2024

Summary

Official Symbol
MANBALprovided by HGNC
Official Full Name
mannosidase beta likeprovided by HGNC
Primary source
HGNC:HGNC:15799
See related
Ensembl:ENSG00000101363 AllianceGenome:HGNC:15799
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in endometrium (RPKM 16.3), adrenal (RPKM 14.8) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See MANBAL in Genome Data Viewer
Location:
20q11.23
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (37289655..37317260)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (39013723..39041331)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (35918058..35945663)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene maestro heat like repeat family member 8 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35807291-35807850 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35807851-35808408 Neighboring gene Sharpr-MPRA regulatory region 9458 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35821940-35822774 Neighboring gene ribophorin II Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35858877-35859417 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:35886402-35886635 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12886 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12887 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35896280-35896826 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35896827-35897374 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17832 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12888 Neighboring gene growth hormone releasing hormone Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17833 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:35918028-35918932 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17834 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35943167-35944074 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35944075-35944984 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:35947577-35948274 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:35964723-35965222 Neighboring gene uncharacterized LOC105372606 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:35968539-35969071 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17836 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17837 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12889 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:35975052-35975552 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17838 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17839 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:35987177-35987747 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17840 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17841 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17842 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17843 Neighboring gene SRC proto-oncogene, non-receptor tyrosine kinase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17844 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12891 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:36019051-36019552 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:36022575-36023431 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:36023432-36024287 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:36024288-36025144 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:36025145-36026001 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:36026002-36026858

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
protein MANBAL
Names
mannosidase beta A like
mannosidase, beta A, lysosomal-like

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003897.2NP_001003897.1  protein MANBAL isoform a

    See identical proteins and their annotated locations for NP_001003897.1

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Related
    ENSP00000362708.3, ENST00000373606.8
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  2. NM_001369742.1NP_001356671.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  3. NM_001369743.1NP_001356672.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  4. NM_001376529.1NP_001363458.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  5. NM_001376530.1NP_001363459.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  6. NM_001376531.1NP_001363460.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  7. NM_001376532.1NP_001363461.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Related
    ENSP00000380339.3, ENST00000397152.7
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  8. NM_001376533.1NP_001363462.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  9. NM_001387335.1NP_001374264.1  protein MANBAL isoform a

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Related
    ENSP00000380338.1, ENST00000397151.1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)
  10. NM_001387336.1NP_001374265.1  protein MANBAL isoform b

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS93036.1
    UniProtKB/TrEMBL
    A2A2E0
    Related
    ENSP00000380337.1, ENST00000397150.5
    Conserved Domains (1) summary
    pfam06783
    Location:749
    UPF0239; Uncharacterized protein family (UPF0239)
  11. NM_001387337.1NP_001374266.1  protein MANBAL isoform b

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS93036.1
    UniProtKB/TrEMBL
    A2A2E0
    Conserved Domains (1) summary
    pfam06783
    Location:749
    UPF0239; Uncharacterized protein family (UPF0239)
  12. NM_001387338.1NP_001374267.1  protein MANBAL isoform b

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS93036.1
    UniProtKB/TrEMBL
    A2A2E0
    Conserved Domains (1) summary
    pfam06783
    Location:749
    UPF0239; Uncharacterized protein family (UPF0239)
  13. NM_001387339.1NP_001374268.1  protein MANBAL isoform b

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS93036.1
    UniProtKB/TrEMBL
    A2A2E0
    Conserved Domains (1) summary
    pfam06783
    Location:749
    UPF0239; Uncharacterized protein family (UPF0239)
  14. NM_022077.4NP_071360.1  protein MANBAL isoform a

    See identical proteins and their annotated locations for NP_071360.1

    Status: VALIDATED

    Source sequence(s)
    AL034422
    Consensus CDS
    CCDS13293.1
    UniProtKB/Swiss-Prot
    A8KAA6, E1P5V3, Q9NQG1
    Conserved Domains (1) summary
    pfam06783
    Location:774
    UPF0239; Uncharacterized protein family (UPF0239)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    37289655..37317260
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791812.1 Reference GRCh38.p14 PATCHES

    Range
    199157..226762
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    39013723..39041331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)