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Ankrd31 ankyrin repeat domain 31 [ Mus musculus (house mouse) ]

Gene ID: 625662, updated on 8-Feb-2024

Summary

Official Symbol
Ankrd31provided by MGI
Official Full Name
ankyrin repeat domain 31provided by MGI
Primary source
MGI:MGI:5006716
See related
Ensembl:ENSMUSG00000109561 AllianceGenome:MGI:5006716
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Involved in homologous chromosome pairing at meiosis; meiotic DNA double-strand break formation involved in reciprocal meiotic recombination; and positive regulation of meiotic DNA double-strand break formation. Located in chromatin. Orthologous to human ANKRD31 (ankyrin repeat domain 31). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 2.4) See more
Orthologs
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Genomic context

See Ankrd31 in Genome Data Viewer
Location:
13; 13 D1
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (96884797..97046302)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (96748289..96909794)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E748 Neighboring gene STARR-seq mESC enhancer starr_35346 Neighboring gene 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Neighboring gene STARR-seq mESC enhancer starr_35347 Neighboring gene STARR-positive B cell enhancer ABC_E9154 Neighboring gene predicted gene, 33171 Neighboring gene predicted gene, 57606 Neighboring gene STARR-seq mESC enhancer starr_35351 Neighboring gene STARR-seq mESC enhancer starr_35353 Neighboring gene glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase) Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:97735001-97735184 Neighboring gene predicted gene, 41027

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General protein information

Preferred Names
ankyrin repeat domain-containing protein 31

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370928.1NP_001357857.1  ankyrin repeat domain-containing protein 31

    Status: VALIDATED

    Source sequence(s)
    AC154851, AC174082
    UniProtKB/Swiss-Prot
    A0A140LI88, A0A140LIB3
    UniProtKB/TrEMBL
    A0A4W7PWM5
    Related
    ENSMUSP00000146720.2, ENSMUST00000208758.2
    Conserved Domains (5) summary
    COG0666
    Location:424628
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:11631193
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11671259
    Ank_2; Ankyrin repeats (3 copies)
    pfam18755
    Location:16941785
    RAMA; Restriction Enzyme Adenine Methylase Associated
    cl39094
    Location:12331300
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    96884797..97046302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247341.1XP_030103201.1  ankyrin repeat domain-containing protein 31 isoform X1

    UniProtKB/Swiss-Prot
    A0A140LI88, A0A140LIB3
    UniProtKB/TrEMBL
    A0A4W7PWM5
    Related
    ENSMUSP00000146751.2, ENSMUST00000207464.2
    Conserved Domains (5) summary
    COG0666
    Location:424628
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:11631193
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:11671259
    Ank_2; Ankyrin repeats (3 copies)
    pfam18755
    Location:16941785
    RAMA; Restriction Enzyme Adenine Methylase Associated
    cl39094
    Location:12331300
    Ank_2; Ankyrin repeats (3 copies)