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Cldn34b4 claudin 34B4 [ Mus musculus (house mouse) ]

Gene ID: 619294, updated on 17-Aug-2024

Summary

Official Symbol
Cldn34b4provided by MGI
Official Full Name
claudin 34B4provided by MGI
Primary source
MGI:MGI:3588232
See related
Ensembl:ENSMUSG00000073085 AllianceGenome:MGI:3588232
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930428D18Rik
Summary
Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN34 (claudin 34). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 5.7) See more
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Genomic context

Location:
X A7.3; X 38.3 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (75428929..75441585)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (76385323..76397979)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 58 pseudogene Neighboring gene MAGE family member A7, pseudogene Neighboring gene STARR-seq mESC enhancer starr_47398 Neighboring gene STARR-seq mESC enhancer starr_47399 Neighboring gene STARR-seq mESC enhancer starr_47400 Neighboring gene STARR-seq mESC enhancer starr_47401 Neighboring gene predicted pseudogene 5793 Neighboring gene claudin 34D

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033799.2NP_001028971.1  claudin 34B4

    See identical proteins and their annotated locations for NP_001028971.1

    Status: VALIDATED

    Source sequence(s)
    AK132827
    Consensus CDS
    CCDS53116.1
    UniProtKB/TrEMBL
    Q3V0X2
    Related
    ENSMUSP00000098964.2, ENSMUST00000101419.2
    Conserved Domains (1) summary
    cl21598
    Location:19198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  2. NM_001356396.1NP_001343325.1  claudin 34B4

    Status: VALIDATED

    Source sequence(s)
    AL672017, BC147626
    Consensus CDS
    CCDS53116.1
    UniProtKB/TrEMBL
    Q3V0X2
    Conserved Domains (1) summary
    cl21598
    Location:19198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    75428929..75441585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006528213.2XP_006528276.1  claudin 34B4 isoform X1

    See identical proteins and their annotated locations for XP_006528276.1

    UniProtKB/TrEMBL
    Q3V0X2
    Related
    ENSMUSP00000159557.1, ENSMUST00000249074.1
    Conserved Domains (1) summary
    cl21598
    Location:19198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family