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LOC6052556 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [ Culex quinquefasciatus (southern house mosquito) ]

Gene ID: 6052556, updated on 26-Mar-2024

Summary

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Gene symbol
LOC6052556
Gene description
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
See related
VectorBase:CQUJHB003663; EnsemblRapid:LOC6052556
Gene type
protein coding
RefSeq status
MODEL
Organism
Culex quinquefasciatus
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Culicinae; Culicini; Culex; Culex
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Genomic context

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Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
100 current VPISU_Cqui_1.0_pri_paternal (GCF_015732765.1) 3 NC_051863.1 (101007..119524, complement)

Chromosome 3 - NC_051863.1Genomic Context describing neighboring genes Neighboring gene lethal (3) 73Ah Neighboring gene threonine aspartase 1 Neighboring gene uncharacterized LOC119768766 Neighboring gene girdin Neighboring gene TRAPP subunit 20

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_051863.1 Chromosome 3 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
Names
phospholipase c epsilon

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Culex quinquefasciatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

Genomic

  1. NC_051863.1 Reference VPISU_Cqui_1.0_pri_paternal Primary Assembly

    Range
    101007..119524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038259832.1 → XP_038115760.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

    UniProtKB/TrEMBL
    B0XGN4
    Related
    XP_038115760.1, XM_038259832.1
    Conserved Domains (7) summary
    PLN02952
    Location:1006 → 1631
    PLN02952; phosphoinositide phospholipase C
    cd15898
    Location:841 → 870
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:841 → 1014
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cd17114
    Location:1680 → 1775
    RA_PLC-epsilon; Ras-associating (RA) domain found in Phosphatidylinositide-specific phospholipase C (PLC)-epsilon
    cl02485
    Location:250 → 375
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cl14615
    Location:1029 → 1482
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl28922
    Location:1829 → 1919
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  2. XM_038259834.1 → XP_038115762.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

    UniProtKB/TrEMBL
    B0XGN4
    Related
    XP_038115762.1, XM_038259834.1
    Conserved Domains (7) summary
    PLN02952
    Location:1006 → 1631
    PLN02952; phosphoinositide phospholipase C
    cd15898
    Location:841 → 870
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:841 → 1014
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cd17114
    Location:1680 → 1775
    RA_PLC-epsilon; Ras-associating (RA) domain found in Phosphatidylinositide-specific phospholipase C (PLC)-epsilon
    cl02485
    Location:250 → 375
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cl14615
    Location:1029 → 1482
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl28922
    Location:1829 → 1919
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  3. XM_038259833.1 → XP_038115761.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

    UniProtKB/TrEMBL
    B0XGN4
    Related
    XP_038115761.1, XM_038259833.1
    Conserved Domains (7) summary
    PLN02952
    Location:1006 → 1631
    PLN02952; phosphoinositide phospholipase C
    cd15898
    Location:841 → 870
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:841 → 1014
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cd17114
    Location:1680 → 1775
    RA_PLC-epsilon; Ras-associating (RA) domain found in Phosphatidylinositide-specific phospholipase C (PLC)-epsilon
    cl02485
    Location:250 → 375
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cl14615
    Location:1029 → 1482
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl28922
    Location:1829 → 1919
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  4. XM_038259831.1 → XP_038115759.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

    UniProtKB/TrEMBL
    B0XGN4
    Related
    XP_038115759.1, XM_038259831.1
    Conserved Domains (7) summary
    PLN02952
    Location:1006 → 1631
    PLN02952; phosphoinositide phospholipase C
    cd15898
    Location:841 → 870
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:841 → 1014
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cd17114
    Location:1680 → 1775
    RA_PLC-epsilon; Ras-associating (RA) domain found in Phosphatidylinositide-specific phospholipase C (PLC)-epsilon
    cl02485
    Location:250 → 375
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cl14615
    Location:1029 → 1482
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl28922
    Location:1829 → 1919
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  5. XM_038259835.1 → XP_038115763.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

    UniProtKB/TrEMBL
    B0XGN4
    Related
    XP_038115763.1, XM_038259835.1
    Conserved Domains (7) summary
    PLN02952
    Location:1006 → 1631
    PLN02952; phosphoinositide phospholipase C
    cd15898
    Location:841 → 870
    EFh_PI-PLC; EF-hand motif [structural motif]
    cl28895
    Location:841 → 1014
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cd17114
    Location:1680 → 1775
    RA_PLC-epsilon; Ras-associating (RA) domain found in Phosphatidylinositide-specific phospholipase C (PLC)-epsilon
    cl02485
    Location:250 → 375
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cl14615
    Location:1029 → 1482
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
    cl28922
    Location:1829 → 1919
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein Strain
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