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Myg1 melanocyte proliferating gene 1 [ Mus musculus (house mouse) ]

Gene ID: 60315, updated on 5-Mar-2024

Summary

Official Symbol
Myg1provided by MGI
Official Full Name
melanocyte proliferating gene 1provided by MGI
Primary source
MGI:MGI:1929864
See related
Ensembl:ENSMUSG00000001285 AllianceGenome:MGI:1929864
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gamm1; 0610023A07Rik; 2810433J21Rik; 5830429P19Rik
Summary
Predicted to enable nuclease activity. Acts upstream of or within locomotory exploration behavior. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; eye; hemolymphoid system gland; and male reproductive gland or organ. Orthologous to human MYG1 (MYG1 exonuclease). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 22.9), adrenal adult (RPKM 22.3) and 28 other tissues See more
Orthologs
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Genomic context

Location:
15 F3; 15 57.49 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (102240144..102246574)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102331709..102338139)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5520 Neighboring gene extra spindle pole bodies 1, separase Neighboring gene STARR-positive B cell enhancer ABC_E7421 Neighboring gene STARR-positive B cell enhancer ABC_E7422 Neighboring gene prefoldin 5 Neighboring gene microRNA 12187 Neighboring gene achalasia, adrenocortical insufficiency, alacrimia Neighboring gene STARR-seq mESC enhancer starr_39832 Neighboring gene predicted gene, 36246

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within locomotory exploration behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
MYG1 exonuclease
Names
UPF0160 protein MYG1, mitochondrial
protein Gamm1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021713.2NP_068359.1  MYG1 exonuclease precursor

    See identical proteins and their annotated locations for NP_068359.1

    Status: VALIDATED

    Source sequence(s)
    AF289484, BU851558, CJ180315
    Consensus CDS
    CCDS27879.1
    UniProtKB/Swiss-Prot
    Q9CYX0, Q9JK81
    UniProtKB/TrEMBL
    Q8R038
    Related
    ENSMUSP00000109312.3, ENSMUST00000113682.9
    Conserved Domains (1) summary
    pfam03690
    Location:45365
    UPF0160; uncharacterized protein family (UPF0160)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    102240144..102246574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248679.1XP_030104539.1  MYG1 exonuclease isoform X1

    Conserved Domains (1) summary
    pfam03690
    Location:10251
    UPF0160; Uncharacterized protein family (UPF0160)