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STRIP2 striatin interacting protein 2 [ Homo sapiens (human) ]

Gene ID: 57464, updated on 18-Aug-2020

Summary

Official Symbol
STRIP2provided by HGNC
Official Full Name
striatin interacting protein 2provided by HGNC
Primary source
HGNC:HGNC:22209
See related
Ensembl:ENSG00000128578 MIM:617919
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM40B; FAR11B
Expression
Biased expression in testis (RPKM 7.5), brain (RPKM 4.0) and 9 other tissues See more
Orthologs

Genomic context

See STRIP2 in Genome Data Viewer
Location:
7q32.1
Exon count:
24
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (129434432..129488399)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (129074274..129128240)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene adenosylhomocysteinase like 2 Neighboring gene RNA, U7 small nuclear 16 pseudogene Neighboring gene cell division cycle 26 pseudogene 1 Neighboring gene small nuclear ribonucleoprotein polypeptide G pseudogene 3 Neighboring gene RNA, U1 small nuclear 72, pseudogene Neighboring gene uncharacterized LOC107986848 Neighboring gene small lysine rich protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
striatin-interacting protein 2
Names
FAR11 factor arrest 11 homolog B
family with sequence similarity 40, member B
homolog of yeast FAR11 protein 2
protein FAM40B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134336.2NP_001127808.1  striatin-interacting protein 2 isoform b

    See identical proteins and their annotated locations for NP_001127808.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC009244, BC019064, DA409007
    Consensus CDS
    CCDS47709.1
    UniProtKB/Swiss-Prot
    Q9ULQ0
    Related
    ENSP00000392393.2, ENST00000435494.2
    Conserved Domains (2) summary
    pfam07923
    Location:49326
    N1221; N1221-like protein
    pfam11882
    Location:456751
    DUF3402; Domain of unknown function (DUF3402)
  2. NM_020704.3NP_065755.1  striatin-interacting protein 2 isoform a

    See identical proteins and their annotated locations for NP_065755.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AB032996, AC009244, DA409007
    Consensus CDS
    CCDS34752.1
    UniProtKB/Swiss-Prot
    Q9ULQ0
    Related
    ENSP00000249344.2, ENST00000249344.7
    Conserved Domains (2) summary
    pfam07923
    Location:49338
    N1221; N1221-like protein
    pfam11882
    Location:456779
    DUF3402; Domain of unknown function (DUF3402)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    129434432..129488399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006716069.3XP_006716132.1  striatin-interacting protein 2 isoform X1

    Conserved Domains (2) summary
    pfam07923
    Location:49338
    N1221; N1221-like protein
    pfam11882
    Location:456684
    DUF3402; Domain of unknown function (DUF3402)
  2. XM_017012472.1XP_016867961.1  striatin-interacting protein 2 isoform X6

  3. XM_017012470.1XP_016867959.1  striatin-interacting protein 2 isoform X2

    Conserved Domains (2) summary
    pfam07923
    Location:49338
    N1221; N1221-like protein
    pfam11882
    Location:456625
    DUF3402; Domain of unknown function (DUF3402)
  4. XM_011516435.1XP_011514737.1  striatin-interacting protein 2 isoform X5

    Conserved Domains (2) summary
    pfam07923
    Location:49338
    N1221; N1221-like protein
    pfam11882
    Location:456485
    DUF3402; Domain of unknown function (DUF3402)
  5. XM_011516432.2XP_011514734.1  striatin-interacting protein 2 isoform X3

    Conserved Domains (2) summary
    pfam07923
    Location:1177
    N1221; N1221-like protein
    pfam11882
    Location:295618
    DUF3402; Domain of unknown function (DUF3402)
  6. XM_017012471.1XP_016867960.1  striatin-interacting protein 2 isoform X4

RNA

  1. XR_001744839.2 RNA Sequence

  2. XR_927493.1 RNA Sequence

  3. XR_001744840.1 RNA Sequence

  4. XR_001744841.1 RNA Sequence

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