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Insyn2b inhibitory synaptic factor family member 2B [ Mus musculus (house mouse) ]

Gene ID: 574403, updated on 5-Mar-2024

Summary

Official Symbol
Insyn2bprovided by MGI
Official Full Name
inhibitory synaptic factor family member 2Bprovided by MGI
Primary source
MGI:MGI:3643491
See related
Ensembl:ENSMUSG00000069911 AllianceGenome:MGI:3643491
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm6041; Fam196b; EG574403
Summary
Is expressed in ovary and testis. Orthologous to human INSYN2B (inhibitory synaptic factor family member 2B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in whole brain E14.5 (RPKM 1.9), frontal lobe adult (RPKM 1.7) and 13 other tissues See more
Orthologs
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Genomic context

Location:
11 A4; 11 19.72 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (34264822..34372642)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (34314822..34422642)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene forkhead box I1 Neighboring gene dedicator of cyto-kinesis 2 Neighboring gene RIKEN cDNA 4930403D09 gene Neighboring gene STARR-seq mESC enhancer starr_29144 Neighboring gene STARR-seq mESC enhancer starr_29145 Neighboring gene STARR-seq mESC enhancer starr_29147 Neighboring gene STARR-seq mESC enhancer starr_29148 Neighboring gene STARR-seq mESC enhancer starr_29150 Neighboring gene predicted gene, 29887 Neighboring gene predicted gene, 39681

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Clone Names

  • MGC99845

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in inhibitory postsynaptic potential IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
INSYN2B protein
Names
family with sequence similarity 196, member B
protein FAM196B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025382.2NP_001020553.1  INSYN2B protein

    See identical proteins and their annotated locations for NP_001020553.1

    Status: VALIDATED

    Source sequence(s)
    AL669849, AL671971
    Consensus CDS
    CCDS36127.1
    UniProtKB/Swiss-Prot
    Q6GQV1
    Related
    ENSMUSP00000129183.2, ENSMUST00000165963.9
    Conserved Domains (1) summary
    pfam15265
    Location:3535
    FAM196; FAM196 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    34264822..34372642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006514763.5XP_006514826.1  INSYN2B protein isoform X1

    See identical proteins and their annotated locations for XP_006514826.1

    UniProtKB/Swiss-Prot
    Q6GQV1
    Conserved Domains (1) summary
    pfam15265
    Location:3535
    FAM196; FAM196 family