U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

U90926 cDNA sequence U90926 [ Mus musculus (house mouse) ]

Gene ID: 57425, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
U90926provided by MGI
Official Full Name
cDNA sequence U90926provided by MGI
Primary source
MGI:MGI:1930915
See related
Ensembl:ENSMUSG00000029409 AllianceGenome:MGI:1930915
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Involved in innate immune response. Located in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See U90926 in Genome Data Viewer
Location:
5 E2; 5 46.23 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (92357754..92363211, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (92209895..92215408, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L13 pseudogene Neighboring gene USO1 vesicle docking factor Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:92612573-92612756 Neighboring gene predicted gene, 25290 Neighboring gene predicted gene, 42113 Neighboring gene predicted gene, 42112 Neighboring gene protein phosphatase, EF hand calcium-binding domain 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:92674514-92674783

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. LncRNA U90926 is dispensable for the development of obesity-associated phenotypes in vivo. Sabikunnahar B, et al. Physiol Rep, 2024 Jan. PMID 38171546, Free PMC Article
  2. Cryptosporidium parvum hijacks a host's long noncoding RNA U90926 to evade intestinal epithelial cell-autonomous antiparasitic defense. Graham ML, et al. Front Immunol, 2023. PMID 37346046, Free PMC Article
  3. Long Noncoding RNA U90926 Is Induced in Activated Macrophages, Is Protective in Endotoxic Shock, and Encodes a Novel Secreted Protein. Sabikunnahar B, et al. J Immunol, 2023 Mar 15. PMID 36705532, Free PMC Article
  4. Microglial lnc-U90926 facilitates neutrophil infiltration in ischemic stroke via MDH2/CXCL2 axis. Chen J, et al. Mol Ther, 2021 Sep 1. PMID 33895326, Free PMC Article
  5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cryptosporidium parvum hijacks a host's long noncoding RNA U90926 to evade intestinal epithelial cell-autonomous antiparasitic defense.
    Title: Cryptosporidium parvum hijacks a host's long noncoding RNA U90926 to evade intestinal epithelial cell-autonomous antiparasitic defense.
  2. Long Noncoding RNA U90926 Is Induced in Activated Macrophages, Is Protective in Endotoxic Shock, and Encodes a Novel Secreted Protein.
    Title: Long Noncoding RNA U90926 Is Induced in Activated Macrophages, Is Protective in Endotoxic Shock, and Encodes a Novel Secreted Protein.
  3. Microglial lnc-U90926 facilitates neutrophil infiltration in ischemic stroke via MDH2/CXCL2 axis.
    Title: Microglial lnc-U90926 facilitates neutrophil infiltration in ischemic stroke via MDH2/CXCL2 axis.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in innate immune response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
endotoxic shock protective protein U9-ORF
Names
U9-ORF protein
putative TNF-resistance related protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001416553.1 → NP_001403482.1  endotoxic shock protective protein U9-ORF precursor

    Status: VALIDATED

    Source sequence(s)
    AC125542
    UniProtKB/Swiss-Prot
    O08546
    Related
    ENSMUSP00000159852.1, ENSMUST00000201332.5

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    92357754..92363211 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_020562.1: Suppressed sequence

    Description
    NM_020562.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.

  2. NR_033483.1: Suppressed sequence

    Description
    NR_033483.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O08546.2 GenPept UniProtKB/Swiss-Prot:O08546

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials