Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Psmd8provided by MGI
Official Full Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 8provided by MGI
Primary source: MGI:MGI:1888669
See related: Ensembl:ENSMUSG00000030591 AllianceGenome:MGI:1888669
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 6720456J22Rik
Summary: Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of proteasome accessory complex. Is expressed in brain; nose; skin; and urethra. Orthologous to human PSMD8 (proteasome 26S subunit, non-ATPase 8). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in testis adult (RPKM 136.7), large intestine adult (RPKM 72.0) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 B1; 7 16.94 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (28873612..28880098, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (29174187..29180673, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH124208 (e-PCR)
- UniSTS:161030

RH124225 (e-PCR)
- UniSTS:161047

RH125972 (e-PCR)
- UniSTS:162684

RH124590 (e-PCR)
- UniSTS:161412

RH124194 (e-PCR)
- UniSTS:161016

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome accessory complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome complex	ISO Inferred from Sequence Orthology more info
part_of proteasome regulatory particle	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 8

Names: 26S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; proteasome 26S non-ATPase subunit 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.