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DANCR differentiation antagonizing non-protein coding RNA [ Homo sapiens (human) ]

Gene ID: 57291, updated on 19-Sep-2021

Summary

Official Symbol
DANCRprovided by HGNC
Official Full Name
differentiation antagonizing non-protein coding RNAprovided by HGNC
Primary source
HGNC:HGNC:28964
See related
Ensembl:ENSG00000226950 MIM:614625
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AGU2; ANCR; SNHG13; KIAA0114; lncRNA-ANCR
Summary
This gene produces a long non-coding RNA that functions as a negative regulator of cell differentiation. This transcript associates with enhancer of zeste homolog 2 to repress expression of the runt related transcription factor 2 gene. Increased expression of this transcript may be associated with cancer. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Dec 2016]
Expression
Ubiquitous expression in ovary (RPKM 52.8), thyroid (RPKM 36.9) and 25 other tissues See more
Orthologs
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Genomic context

See DANCR in Genome Data Viewer
Location:
4q12
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (52712394..52720697)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (53578561..53586864)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 46 Neighboring gene USP46 divergent transcript Neighboring gene microRNA 4449 Neighboring gene small nucleolar RNA, H/ACA box 26 Neighboring gene endogenous retrovirus group MER34 member 1, envelope Neighboring gene uncharacterized LOC107986281 Neighboring gene long intergenic non-protein coding RNA 1618

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • adipogenesis up-regulated transcript 2
  • anti-differentiation ncRNA
  • anti-differentiation noncoding RNA
  • small nucleolar RNA host gene 13 (non-protein coding)

Clone Names

  • KIAA0114, KIAA00167

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024031.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript.
    Source sequence(s)
    AC104066, D28589, LC128578
    Related
    ENST00000411630.7
  2. NR_145129.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 3' exon structure and is longer than variant 1.
    Source sequence(s)
    AC104066, LC128578
  3. NR_145130.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 3' exon structure and is longer than variant 1.
    Source sequence(s)
    AC104066, LC128577
    Related
    ENST00000675705.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    52712394..52720697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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