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CAMK1G calcium/calmodulin dependent protein kinase IG [ Homo sapiens (human) ]

Gene ID: 57172, updated on 6-May-2021

Summary

Official Symbol
CAMK1Gprovided by HGNC
Official Full Name
calcium/calmodulin dependent protein kinase IGprovided by HGNC
Primary source
HGNC:HGNC:14585
See related
Ensembl:ENSG00000008118 MIM:614994
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
VWS1; CLICK3; CLICKIII; dJ272L16.1
Summary
This gene encodes a protein similar to calcium/calmodulin dependent protein kinase, however, its exact function is not known. [provided by RefSeq, Jul 2008]
Expression
Biased expression in ovary (RPKM 11.3), brain (RPKM 11.2) and 5 other tissues See more
Orthologs
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Genomic context

See CAMK1G in Genome Data Viewer
Location:
1q32.2
Exon count:
13
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (209583714..209613939)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (209757059..209787284)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372898 Neighboring gene uncharacterized LOC105372899 Neighboring gene uncharacterized LOC107985256 Neighboring gene laminin subunit beta 3 Neighboring gene microRNA 4260 Neighboring gene HSD11B1 antisense RNA 1 Neighboring gene G0/G1 switch 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.
GeneReviews: Not available
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables calmodulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calmodulin-dependent protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
part_of calcium- and calmodulin-dependent protein kinase complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in intracellular anatomical structure IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
calcium/calmodulin-dependent protein kinase type 1G
Names
CLICK III
caM kinase I gamma
caM kinase IG
caM-KI gamma
caMK-like CREB kinase III
caMKI gamma
caMKIG
NP_065172.1
XP_016857355.1
XP_016857356.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020439.3NP_065172.1  calcium/calmodulin-dependent protein kinase type 1G

    See identical proteins and their annotated locations for NP_065172.1

    Status: REVIEWED

    Source sequence(s)
    AL049688, BC032787, BG715920
    Consensus CDS
    CCDS1486.1
    UniProtKB/Swiss-Prot
    Q96NX5
    Related
    ENSP00000354861.2, ENST00000361322.3
    Conserved Domains (1) summary
    cd14166
    Location:19303
    STKc_CaMKI_gamma; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type I gamma

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    209583714..209613939
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001866.2XP_016857355.1  calcium/calmodulin-dependent protein kinase type 1G isoform X1

    UniProtKB/Swiss-Prot
    Q96NX5
    Related
    ENSP00000009105.1, ENST00000009105.5
    Conserved Domains (1) summary
    cd14166
    Location:19303
    STKc_CaMKI_gamma; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type I gamma
  2. XM_017001867.1XP_016857356.1  calcium/calmodulin-dependent protein kinase type 1G isoform X2

    Related
    ENSP00000498823.1, ENST00000651530.1
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