Format

Send to:

Choose Destination

YAE1 YAE1 maturation factor of ABCE1 [ Homo sapiens (human) ]

Gene ID: 57002, updated on 13-Mar-2020

Summary

Official Symbol
YAE1provided by HGNC
Official Full Name
YAE1 maturation factor of ABCE1provided by HGNC
Primary source
HGNC:HGNC:24857
See related
Ensembl:ENSG00000241127
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CIAB2; GK003; YAE1D1; C7orf36
Expression
Ubiquitous expression in testis (RPKM 3.0), endometrium (RPKM 2.4) and 25 other tissues See more
Orthologs

Genomic context

See YAE1 in Genome Data Viewer
Location:
7p14.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (39566404..39612089)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (39605984..39651681)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375237 Neighboring gene uncharacterized LOC105375240 Neighboring gene thioredoxin related transmembrane protein 1 pseudogene Neighboring gene akirin 1 pseudogene Neighboring gene uncharacterized LOC107986785 Neighboring gene RAS like proto-oncogene A Neighboring gene Sharpr-MPRA regulatory region 6412

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ39538

Gene Ontology Provided by GOA

Process Evidence Code Pubs
protein maturation by [4Fe-4S] cluster transfer IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein YAE1 homolog
Names
YAE1, ABCE1 maturation factor
Yae1 domain containing 1
yae1 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001282446.2NP_001269375.1  protein YAE1 homolog isoform 2

    See identical proteins and their annotated locations for NP_001269375.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and 3' coding region compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AA157293, AC004837, AK293511, BM767075
    Consensus CDS
    CCDS64630.1
    UniProtKB/Swiss-Prot
    Q9NRH1
    Related
    ENSP00000395777.2, ENST00000432096.2
    Conserved Domains (1) summary
    pfam09811
    Location:4583
    Yae1_N; Essential protein Yae1, N terminal
  2. NM_020192.5NP_064577.1  protein YAE1 homolog isoform 1

    See identical proteins and their annotated locations for NP_064577.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AF226046, BM767075
    Consensus CDS
    CCDS5459.1
    UniProtKB/Swiss-Prot
    Q9NRH1
    Related
    ENSP00000223273.2, ENST00000223273.7
    Conserved Domains (1) summary
    pfam09811
    Location:4583
    Yae1_N; Essential protein Yae1, N terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    39566404..39612089
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center