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Slc6a14 solute carrier family 6 (neurotransmitter transporter), member 14 [ Mus musculus (house mouse) ]

Gene ID: 56774, updated on 8-Dec-2022

Summary

Official Symbol
Slc6a14provided by MGI
Official Full Name
solute carrier family 6 (neurotransmitter transporter), member 14provided by MGI
Primary source
MGI:MGI:1890216
See related
Ensembl:ENSMUSG00000031089 AllianceGenome:MGI:1890216
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ATB0plus; CATB0plus; 1110007A17Rik; 9030613J17Rik
Summary
Predicted to enable alanine transmembrane transporter activity and amine transmembrane transporter activity. Predicted to be involved in amino acid transport; response to toxic substance; and sodium ion transmembrane transport. Predicted to act upstream of or within amino acid transport. Predicted to be located in brush border membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SLC6A14 (solute carrier family 6 member 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 6.4), lung adult (RPKM 2.1) and 1 other tissue See more
Orthologs
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Genomic context

See Slc6a14 in Genome Data Viewer
Location:
X; X A2
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (21581139..21608597)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (21714900..21742358)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 22592 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene 28269 Neighboring gene predicted gene, 24535

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC150294, MGC150295

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in (R)-carnitine transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in (R)-carnitine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in alanine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in amino acid import across plasma membrane ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within amino acid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in beta-alanine transport ISO
Inferred from Sequence Orthology
more info
 
involved_in response to toxic substance ISO
Inferred from Sequence Orthology
more info
 
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in brush border membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
Names
amino acid transporter ATB0+
colonic system B0+ amino acid transporter CATB0+
solute carrier family 6 member 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020049.4NP_064433.3  sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

    See identical proteins and their annotated locations for NP_064433.3

    Status: VALIDATED

    Source sequence(s)
    AL807250, BC129908
    Consensus CDS
    CCDS30051.1
    UniProtKB/Swiss-Prot
    Q9JMA9, Q9R183
    UniProtKB/TrEMBL
    A1L359
    Related
    ENSMUSP00000033414.8, ENSMUST00000033414.8
    Conserved Domains (1) summary
    cl00456
    Location:36637
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    21581139..21608597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)