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CABP5 calcium binding protein 5 [ Homo sapiens (human) ]

Gene ID: 56344, updated on 7-Jun-2020

Summary

Official Symbol
CABP5provided by HGNC
Official Full Name
calcium binding protein 5provided by HGNC
Primary source
HGNC:HGNC:13714
See related
Ensembl:ENSG00000105507 MIM:607315
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CABP3
Summary
The product of this gene belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of this gene is retina-specific. The mouse homolog of this protein has been shown to express in the inner nuclear layer of the retina, suggested its role in neuronal functioning. The specific function of this gene is unknown. [provided by RefSeq, Oct 2009]
Expression
Ubiquitous expression in adrenal (RPKM 2.1), brain (RPKM 1.8) and 23 other tissues See more
Orthologs

Genomic context

See CABP5 in Genome Data Viewer
Location:
19q13.33
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (48029383..48048342, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (48532640..48547311, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene binder of sperm protein homolog 1 Neighboring gene epididymal sperm binding protein 1 Neighboring gene phospholipase A2 group IVC Neighboring gene PLA2G4C antisense RNA 1 Neighboring gene DNA ligase 1 Neighboring gene uncharacterized LOC107985293

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium ion binding NAS
Non-traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
calcium-binding protein 5
Names
calcium-binding protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019855.5NP_062829.1  calcium-binding protein 5

    See identical proteins and their annotated locations for NP_062829.1

    Status: REVIEWED

    Source sequence(s)
    AA318398, AC010330, AC010458, AF169159, BU734136
    Consensus CDS
    CCDS12709.1
    UniProtKB/Swiss-Prot
    Q9NP86
    Related
    ENSP00000293255.1, ENST00000293255.3
    Conserved Domains (1) summary
    cl25352
    Location:25171
    EFh_PEF; The penta-EF hand (PEF) family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    48029383..48048342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026992.1XP_016882481.1  calcium-binding protein 5 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_016367.1: Suppressed sequence

    Description
    NM_016367.1: This RefSeq was permanently suppressed because it contains the wrong CDS.
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