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MOSPD1 motile sperm domain containing 1 [ Homo sapiens (human) ]

Gene ID: 56180, updated on 10-Dec-2019

Summary

Official Symbol
MOSPD1provided by HGNC
Official Full Name
motile sperm domain containing 1provided by HGNC
Primary source
HGNC:HGNC:25235
See related
Ensembl:ENSG00000101928 MIM:300674
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DJ473B4
Expression
Ubiquitous expression in endometrium (RPKM 7.2), adrenal (RPKM 6.2) and 25 other tissues See more
Orthologs

Genomic context

See MOSPD1 in Genome Data Viewer
Location:
Xq26.3
Exon count:
8
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (134887626..134915314, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (134021656..134049314, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene placenta enriched 1 Neighboring gene RNA, U4 small nuclear 44, pseudogene Neighboring gene family with sequence similarity 122B Neighboring gene family with sequence similarity 122C Neighboring gene RNA, U6 small nuclear 616, pseudogene Neighboring gene long intergenic non-protein coding RNA 2243

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
motile sperm domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001306188.2NP_001293117.1  motile sperm domain-containing protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001293117.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks a 3' coding exon but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
    Source sequence(s)
    BC005700, CB997365, CN428237
    Consensus CDS
    CCDS78507.1
    UniProtKB/Swiss-Prot
    Q9UJG1
    Related
    ENSP00000359815.4, ENST00000370779.8
    Conserved Domains (1) summary
    pfam00635
    Location:16115
    Motile_Sperm; MSP (Major sperm protein) domain
  2. NM_019556.3NP_062456.1  motile sperm domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_062456.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC005700, CN428237
    Consensus CDS
    CCDS14645.1
    UniProtKB/Swiss-Prot
    Q9UJG1
    Related
    ENSP00000359819.3, ENST00000370783.8
    Conserved Domains (1) summary
    pfam00635
    Location:16115
    Motile_Sperm; MSP (Major sperm protein) domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    134887626..134915314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029653.1XP_016885142.1  motile sperm domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9UJG1
    Conserved Domains (1) summary
    pfam00635
    Location:16115
    Motile_Sperm; MSP (Major sperm protein) domain
  2. XM_017029654.1XP_016885143.1  motile sperm domain-containing protein 1 isoform X2

    UniProtKB/Swiss-Prot
    Q9UJG1
    Conserved Domains (1) summary
    pfam00635
    Location:16115
    Motile_Sperm; MSP (Major sperm protein) domain
  3. XM_011531366.2XP_011529668.1  motile sperm domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011529668.1

    UniProtKB/Swiss-Prot
    Q9UJG1
    Conserved Domains (1) summary
    pfam00635
    Location:16115
    Motile_Sperm; MSP (Major sperm protein) domain
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