U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

DNAJC11 DnaJ heat shock protein family (Hsp40) member C11 [ Homo sapiens (human) ]

Gene ID: 55735, updated on 19-Sep-2024

Summary

Official Symbol
DNAJC11provided by HGNC
Official Full Name
DnaJ heat shock protein family (Hsp40) member C11provided by HGNC
Primary source
HGNC:HGNC:25570
See related
Ensembl:ENSG00000007923 MIM:614827; AllianceGenome:HGNC:25570
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
dJ126A5.1
Summary
Involved in cristae formation. Located in mitochondrial outer membrane and nuclear speck. Part of MIB complex. Colocalizes with MICOS complex and SAM complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney (RPKM 23.0), colon (RPKM 15.3) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See DNAJC11 in Genome Data Viewer
Location:
1p36.31
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (6634170..6701816, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (6159834..6227482, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (6694230..6761876, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984913 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 87 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 86 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 88 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:6664299-6664647 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 167 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 168 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 169 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 170 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 171 Neighboring gene PHD finger protein 13 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 172 Neighboring gene THAP domain containing 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:6706173-6706672 Neighboring gene Sharpr-MPRA regulatory region 8512 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 173 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:6774349-6775170 Neighboring gene long intergenic non-protein coding RNA 1672 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ10737

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cristae formation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cristae formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in inner mitochondrial membrane organization IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
dnaJ homolog subfamily C member 11
Names
DnaJ (Hsp40) homolog, subfamily C, member 11
novel DnaJ domain-containing protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018198.4NP_060668.2  dnaJ homolog subfamily C member 11

    See identical proteins and their annotated locations for NP_060668.2

    Status: VALIDATED

    Source sequence(s)
    AF306695, AL031447, AL159177, DB461237
    Consensus CDS
    CCDS87.1
    UniProtKB/Swiss-Prot
    Q4VWF5, Q5VZN0, Q6PK20, Q6PK70, Q8NDM2, Q96CL7, Q9NVH1
    UniProtKB/TrEMBL
    B4DPK2
    Related
    ENSP00000366800.5, ENST00000377577.10
    Conserved Domains (2) summary
    pfam00226
    Location:1479
    DnaJ; DnaJ domain
    pfam11875
    Location:417549
    DUF3395; Domain of unknown function (DUF3395)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    6634170..6701816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047424842.1XP_047280798.1  dnaJ homolog subfamily C member 11 isoform X1

    UniProtKB/TrEMBL
    B4DGD5, B4DPK2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    6159834..6227482 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054337587.1XP_054193562.1  dnaJ homolog subfamily C member 11 isoform X1

    UniProtKB/TrEMBL
    B4DGD5, B4DPK2