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BCAS4 breast carcinoma amplified sequence 4 [ Homo sapiens (human) ]

Gene ID: 55653, updated on 23-Nov-2021

Summary

Official Symbol
BCAS4provided by HGNC
Official Full Name
breast carcinoma amplified sequence 4provided by HGNC
Primary source
HGNC:HGNC:14367
See related
Ensembl:ENSG00000124243 MIM:607471
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CNOL
Expression
Broad expression in lymph node (RPKM 5.4), appendix (RPKM 2.0) and 18 other tissues See more
Orthologs
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Genomic context

See BCAS4 in Genome Data Viewer
Location:
20q13.13
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (50794894..50877736)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (49411431..49493714)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr20.2420 Neighboring gene par-6 family cell polarity regulator beta Neighboring gene TMSB4X pseudogene 6 Neighboring gene activity dependent neuroprotector homeobox Neighboring gene proteasome 26S subunit, non-ATPase, 10 pseudogene 1 Neighboring gene ADNP antisense RNA 1 Neighboring gene dolichyl-phosphate mannosyltransferase subunit 1, catalytic

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20495

Gene Ontology Provided by GOA

Component Evidence Code Pubs
part_of BLOC-1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
breast carcinoma-amplified sequence 4
Names
BCAS4/BCAS3 fusion
breast carcinoma amplified sequence 4/3 fusion protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001010974.2NP_001010974.1  breast carcinoma-amplified sequence 4 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate exons in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (c) has a distinct C-terminus and is shorter than isoform a.
    Source sequence(s)
    AF361220, BC056883, BP212127
    UniProtKB/Swiss-Prot
    Q8TDM0
  2. NM_017843.4NP_060313.3  breast carcinoma-amplified sequence 4 isoform a

    See identical proteins and their annotated locations for NP_060313.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longest isoform (a).
    Source sequence(s)
    AF361220, BC056883, BP212127
    Consensus CDS
    CCDS33487.1
    UniProtKB/Swiss-Prot
    Q8TDM0
    Related
    ENSP00000351642.5, ENST00000358791.9
  3. NM_198799.4NP_942094.3  breast carcinoma-amplified sequence 4 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.
    Source sequence(s)
    AL031680, AL133228
    Consensus CDS
    CCDS13432.2
    Related
    ENSP00000360669.3, ENST00000371608.8

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    50794894..50877736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011528887.2XP_011527189.1  breast carcinoma-amplified sequence 4 isoform X2

    See identical proteins and their annotated locations for XP_011527189.1

    UniProtKB/Swiss-Prot
    Q8TDM0
  2. XM_011528886.2XP_011527188.1  breast carcinoma-amplified sequence 4 isoform X1

  3. XM_017027932.1XP_016883421.1  breast carcinoma-amplified sequence 4 isoform X3

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