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slc5a8l solute carrier family 5 member 8, like [ Danio rerio (zebrafish) ]

Gene ID: 556156, updated on 27-Mar-2024

Summary

Official Symbol
slc5a8lprovided by ZNC
Official Full Name
solute carrier family 5 member 8, likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061110-98
See related
Ensembl:ENSDARG00000003697 AllianceGenome:ZFIN:ZDB-GENE-061110-98
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
smcte; slc5a8; wu:fd59e02; zgc:152716
Summary
Enables secondary active monocarboxylate transmembrane transporter activity. Predicted to be involved in sodium ion transport. Predicted to act upstream of or within ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including immature eye; male organism; nervous system; neurocranial trabecula; and pleuroperitoneal region. Orthologous to human SLC5A8 (solute carrier family 5 member 8). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

See slc5a8l in Genome Data Viewer
Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (49063289..49078263, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (49064636..49079610, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 16 member 1a Neighboring gene si:ch211-105j21.9 Neighboring gene synaptonemal complex protein 1 Neighboring gene thyroid stimulating hormone subunit beta a Neighboring gene solute carrier family 25 member 55a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables monocarboxylate:sodium symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables organic acid:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables secondary active monocarboxylate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in acetate transport ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within carboxylic acid transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in chloride transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in iodide transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in lactate transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within monocarboxylic acid transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nicotinate transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nitrate transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in propanoate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in propanoate transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in pyruvate transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in sodium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sodium-coupled monocarboxylate transporter 1
Names
electrogenic sodium monocarboxylate cotransporter
sodium solute symporter family 5 member 8 protein
solute carrier family 5 (iodide transporter), member 8-like
zSMCTe

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034969.1NP_001030141.1  sodium-coupled monocarboxylate transporter 1

    See identical proteins and their annotated locations for NP_001030141.1

    Status: PROVISIONAL

    Source sequence(s)
    AY727859
    UniProtKB/Swiss-Prot
    A0AUP7, Q3ZMH1
    Related
    ENSDARP00000030637.6, ENSDART00000032982.8
    Conserved Domains (1) summary
    cd11519
    Location:8547
    SLC5sbd_SMCT1; Na(+)/monocarboxylate cotransporter SMCT1 and related proteins; solute-binding domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    49063289..49078263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394668.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    164684..179124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)