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KCNQ1DN KCNQ1 downstream neighbor [ Homo sapiens (human) ]

Gene ID: 55539, updated on 23-Nov-2021

Summary

Official Symbol
KCNQ1DNprovided by HGNC
Official Full Name
KCNQ1 downstream neighborprovided by HGNC
Primary source
HGNC:HGNC:13335
See related
Ensembl:ENSG00000237941 MIM:610980
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BWRT; HSA404617
Summary
Imprinting is a phenomenon in which epigenetic modifications lead to expression or suppression of alleles of some genes based on their parental origin. Wilms tumor-2 (WT2; MIM 194071) is defined by maternal-specific loss of heterozygosity of a critical region on chromosome 11p15.5 that includes several imprinted genes. KCNQ1DN is an imprinted gene located within the WT2 critical region that is expressed from the maternal allele (Xin et al., 2000 [PubMed 11056398]).[supplied by OMIM, Mar 2008]
Expression
Restricted expression toward testis (RPKM 1.3) See more
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Genomic context

See KCNQ1DN in Genome Data Viewer
Location:
11p15.4; 11p15.5
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (2870033..2872105)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (2891263..2893335)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel subfamily Q member 1 Neighboring gene KCNQ1 antisense RNA 1 Neighboring gene CRISPRi-validated cis-regulatory element chr11.592 Neighboring gene SLC22A18 antisense RNA Neighboring gene cyclin dependent kinase inhibitor 1C Neighboring gene solute carrier family 22 member 18

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Other Names

  • KCNQ1 downstream neighbor (non-protein coding)

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024627.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AB039920
    Related
    ENST00000441418.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    2870033..2872105
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187585.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    102228..104278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_018722.2: Suppressed sequence

    Description
    NM_018722.2: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
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