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NPY4R neuropeptide Y receptor Y4 [ Homo sapiens (human) ]

Gene ID: 5540, updated on 21-Dec-2019

Summary

Official Symbol
NPY4Rprovided by HGNC
Official Full Name
neuropeptide Y receptor Y4provided by HGNC
Primary source
HGNC:HGNC:9329
See related
Ensembl:ENSG00000204174 MIM:601790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Y4; PP1; PPYR1; NPY4-R
Expression
Biased expression in colon (RPKM 2.9), skin (RPKM 1.7) and 7 other tissues See more
Orthologs

Genomic context

See NPY4R in Genome Data Viewer
Location:
10q11.22
Exon count:
5
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (46458548..46470694, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (47083534..47088320)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4-like Neighboring gene uncharacterized LOC107987152 Neighboring gene long intergenic non-protein coding RNA 842 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 33 Neighboring gene uncharacterized LOC101927699 Neighboring gene G protein regulated inducer of neurite outgrowth 2 Neighboring gene Sharpr-MPRA regulatory regions 2784 and 8617 duplicate 1 Neighboring gene synaptotagmin 15

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC116897

General protein information

Preferred Names
neuropeptide Y receptor type 4
Names
pancreatic polypeptide receptor 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278794.1NP_001265723.1  neuropeptide Y receptor type 4

    See identical proteins and their annotated locations for NP_001265723.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC244230
    Consensus CDS
    CCDS73100.1
    UniProtKB/Swiss-Prot
    P50391
    Related
    ENSP00000480883.1, ENST00000612632.3
    Conserved Domains (1) summary
    pfam00001
    Location:58322
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. NM_005972.6NP_005963.4  neuropeptide Y receptor type 4

    See identical proteins and their annotated locations for NP_005963.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC244230
    Consensus CDS
    CCDS73100.1
    UniProtKB/Swiss-Prot
    P50391
    Related
    ENSP00000363431.1, ENST00000374312.5
    Conserved Domains (1) summary
    pfam00001
    Location:58322
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    46458548..46470694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011539936.3XP_011538238.1  neuropeptide Y receptor type 4 isoform X1

    See identical proteins and their annotated locations for XP_011538238.1

    UniProtKB/Swiss-Prot
    P50391
    Conserved Domains (1) summary
    pfam00001
    Location:58322
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  2. XM_011539937.3XP_011538239.1  neuropeptide Y receptor type 4 isoform X1

    See identical proteins and their annotated locations for XP_011538239.1

    UniProtKB/Swiss-Prot
    P50391
    Conserved Domains (1) summary
    pfam00001
    Location:58322
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  3. XM_017016387.2XP_016871876.1  neuropeptide Y receptor type 4 isoform X1

    UniProtKB/Swiss-Prot
    P50391
    Conserved Domains (1) summary
    pfam00001
    Location:58322
    7tm_1; 7 transmembrane receptor (rhodopsin family)
  4. XM_017016386.2XP_016871875.1  neuropeptide Y receptor type 4 isoform X1

    UniProtKB/Swiss-Prot
    P50391
    Conserved Domains (1) summary
    pfam00001
    Location:58322
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RNA

  1. XR_001747123.2 RNA Sequence

  2. XR_001747124.2 RNA Sequence

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