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PPP4R1L protein phosphatase 4 regulatory subunit 1 like (pseudogene) [ Homo sapiens (human) ]

Gene ID: 55370, updated on 24-Nov-2020

Summary

Official Symbol
PPP4R1Lprovided by HGNC
Official Full Name
protein phosphatase 4 regulatory subunit 1 like (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:15755
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRO1085; PPP4R1P1; C20orf192
Annotation information
Note: Although this gene was previously annotated as a protein-coding locus, it appears to be a pseudogene of PPP4R1 (GeneID: 9989) because the CDS is disrupted by a nonsense mutation that truncates the protein after 415-aa. Consequently, transcripts are candidates for nonsense-mediated decay (NMD). [13 Feb 2013]
Expression
Ubiquitous expression in ovary (RPKM 3.1), testis (RPKM 3.1) and 24 other tissues See more

Genomic context

See PPP4R1L in Genome Data Viewer
Location:
20q13.32
Exon count:
17
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (58232777..58309439, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (56807833..56884495, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372694 Neighboring gene ankyrin repeat domain 60 Neighboring gene RAB22A, member RAS oncogene family Neighboring gene VAMP associated protein B and C

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Other Names

  • protein phosphatase 4, regulatory subunit 1 pseudogene
  • protein phosphatase 4, regulatory subunit 1-like

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein phosphatase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
protein serine/threonine phosphatase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003505.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK057583, AL354776

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    58232777..58309439 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_018498.2: Suppressed sequence

    Description
    NM_018498.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
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