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CCDC87 coiled-coil domain containing 87 [ Homo sapiens (human) ]

Gene ID: 55231, updated on 25-Jan-2022

Summary

Official Symbol
CCDC87provided by HGNC
Official Full Name
coiled-coil domain containing 87provided by HGNC
Primary source
HGNC:HGNC:25579
See related
Ensembl:ENSG00000182791 AllianceGenome:HGNC:25579
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in positive regulation of acrosome reaction and positive regulation of fertilization. [provided by Alliance of Genome Resources, Nov 2021]
Orthologs
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Genomic context

See CCDC87 in Genome Data Viewer
Location:
11q13.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (66590176..66593063, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (66357647..66360534, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene actinin alpha 3 Neighboring gene cathepsin F Neighboring gene copper chaperone for superoxide dismutase Neighboring gene RNA, U4 small nuclear 39, pseudogene

Genomic regions, transcripts, and products

Phenotypes

EBI GWAS Catalog

Description
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ10786

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of acrosome reaction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of fertilization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in single fertilization IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 87

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018219.3NP_060689.2  coiled-coil domain-containing protein 87

    See identical proteins and their annotated locations for NP_060689.2

    Status: VALIDATED

    Source sequence(s)
    AI391530, AK001648, AP001157
    Consensus CDS
    CCDS8145.1
    UniProtKB/Swiss-Prot
    Q9NVE4
    Related
    ENSP00000328487.3, ENST00000333861.5
    Conserved Domains (1) summary
    pfam03999
    Location:711833
    MAP65_ASE1; Microtubule associated protein (MAP65/ASE1 family)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    66590176..66593063 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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